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Analgesic/Antitussive/Decongestant/Expectorant Combination


Treats fever, headache, sore throat, body aches, sneezing, runny and stuffy nose, and cough. May also help to loosen mucus in upper airways.

Brand Names

Tylenol Cold Severe Congestion
Robitussin Cold Cough &
Comtrex Deep Chest Cold
Multi-Symptom Severe Cold Congestion
Sudafed PE Cold &
Tylenol Cold Head Congestion Severe
Tylenol Cold Severe Head Congestion
Tylenol Cold Multi-Symptom
Leader Pain Relief Cold PE
Tylenol Cold Multi-Symptom Severe

When You Should Not Take The Medication

You should not use this medicine if you have had an allergic reaction to acetaminophen (Tylenol®), or to any other ingredients in the medicine you are using.

How To Store And Dispose Of This Medicine

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

Keep all medicine away from children and never share your medicine with anyone.

Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:
Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing.
If your symptoms do not improve or if they get worse, call your doctor.
Fever that lasts for a long time or a fever that does not go away.

If you notice these less serious side effects, talk with your doctor:
Cough that lasts for a long time or a cough that does not go away.
New symptoms.
Redness of your throat or swelling around your throat.
Trouble passing urine.

If you notice other side effects that you think are caused by this medicine, tell your doctor.