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Guaifenesin and Potassium guaiacolsulfonate oral

Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.


(gweye-FEN-eh-sin/poh-TASS-ee-um GWEYE-uh-koll-SULL-fun-ate)



Guaifenesin is an expectorant which helps to loosen mucus. Potassium guaiacolsulfonate is also an expectorant. This combination medication is used to treat a cough associated with the common cold, asthma, and other respiratory illnesses (e.g., sinusitis, pharyngitis, bronchitis).

How To Use

Take this medication twice daily (12 hours apart); or as directed by your doctor. It is best to swallow the medicine whole. Do not crush or chew this medication. Take this medication with a full glass of water. Water will also help break-up the mucous and clear congestion. Drink plenty of fluids while taking this medication, unless your doctor instructs you otherwise. Do not take this medication for a chronic, persistent cough such as occurs with smoking unless directed by your doctor. If the cough last for more than one week, tends to recur, or is accompanied by a fever, headache or rash, consult your doctor.

Side Effects

Nausea, vomiting, stomach upset, dizziness, headache, rash, or hives may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Tell your doctor immediately if any of these unlikely but serious side effects occur: painful urination (with fever and chills), blood in urine. If you notice other effects not listed above, contact your doctor or pharmacist.


Before using this medication, tell your doctor or pharmacist your medical history, especially of: breathing problems (such as emphysema/chronic bronchitis/asthma), smoking, any allergies. This drug may make you dizzy; use caution engaging in activities requiring alertness such as driving or using machinery. Limit alcoholic beverages. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding.

Drug Interactions

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: other cough-and-cold medicines. This product can affect the results of certain lab tests. Make sure laboratory personnel and your doctors know you use this drug. Do not start or stop any medicine without doctor or pharmacist approval.


If overdose is suspected, contact your local poison control center or emergency room immediately.


Do not share this medication with others.

Missed Dose

If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.


Store at room temperature between 68 and 77 degrees F (20-25 degrees C) away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets.