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Etodolac oral

Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.





Etodolac is used to treat the pain and swelling associated with conditions such as arthritis, bursitis and tendonitis.

How To Use

Take exactly as directed to minimize the risk of side effects. Take with food. Swallow tablets whole. Do not crush or chew them. This medication is usually taken once daily. Take this medication with 6 to 8 ounces (180-240ml) of water. Do not lie down for at least 30 minutes after taking this drug. In arthritis, it may take one to two weeks before the full effects of this medication are noted. For best results, this should be taken regularly as directed by your doctor.

Side Effects

Many side effects observed are mild and usually disappear after a short time. Diarrhea, gas, constipation, upset stomach or headache may occur. If these effects persist or worsen, notify your doctor. Unlikely but report promptly: vision changes, yellowing of the skin or eyes, fever, mood changes, dizziness, ringing in the ears. Very unlikely but report: unusual bleeding or bruising, persistent sore throat, unusual change in urine amount. If you notice any of the following unlikely but very serious side effects, stop taking this drug and consult your doctor or pharmacist immediately: black stools, persistent stomach/ abdominal pain, vomit that looks like coffee grounds. In the unlikely event you have an allergic reaction to this drug, seek immediate medical attention. Symptoms of an allergic reaction include: rash, itching, swelling, severe dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.


Tell your doctor your medical history, especially of: liver or kidney disease, blood disorders, ulcers, heart disease, alcohol use, high blood pressure, eye disease, asthma, nasal polyps, any allergies - especially aspirin/NSAID allergy (e.g., ibuprofen, celecoxib). Use caution when performing tasks requiring alertness. Limit alcohol intake as it may intensify the drowsiness effect of this medication. This medicine may cause stomach bleeding. Daily use of alcohol, especially when combined with this medicine, may increase your risk for stomach bleeding. Check with your doctor or pharmacist for more information. Infrequently, this medication may increase the skin's sensitivity to sunlight. If this happens to you, avoid prolonged sun exposure, wear protective clothing and use a sunscreen. Avoid sunlamps. Caution is advised when this drug is used in the elderly. This medication should be used during pregnancy only if clearly needed. Discuss the risks and benefits with your doctor. Use of this drug in the last 6 months of pregnancy is not recommended. It is unknown if etodolac is excreted into breast milk. Consult your doctor before breast-feeding.

Drug Interactions

Tell your doctor or pharmacist of all the other drugs you take (both prescription and nonprescription), especially of: blood thinners (warfarin), other arthritis drugs, drugs used for inflammation (including aspirin), methotrexate, water pills, digoxin, lithium, cyclosporine. Do not take aspirin without consulting your doctor. Check the ingredients of all nonprescription medications you may be taking since many cough-and-cold formulas contain aspirin. Do not start or stop any medicine without doctor or pharmacist approval.


If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include severe stomach pain, coffee ground-like vomit, dark stool, ringing in the ears, change in amount of urine, unusually fast or slow heartbeat, muscle weakness, slow or shallow breathing, confusion, severe headache or loss of consciousness.


Do not allow anyone else to use this medication. Your doctor may monitor kidney, liver and blood cell test periodically. False-positive results for urine tests (bilirubin and ketones) may occur when taking etodolac.

Missed Dose

If you miss a dose, take it as soon as remembered but not if it is almost time for the next dose. Instead, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.


Store this medication at controlled room temperature between 68 to 77 degrees F (20-25 degrees C) away from heat, light and moisture. Do not store in the bathroom.