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Ethionamide oral

Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.





This medication is used to treat tuberculosis in combination with other anti-tuberculosis drugs.



This drug may also be used for treating other mycobacterial infections.

How To Use

Take by mouth exactly as directed, from one to three times per day for a minimum of 6 months. Follow your medication label instructions. Antibiotics work best when the amount of medicine in your body is kept at a constant level. Do this by taking the medication at evenly spaced intervals throughout the day and night. It is critical to take this medication and the other TB drugs until the full prescribed treatment is finished even if symptoms have disappeared. Stopping the medication too early will allow bacteria to continue to grow resulting in a relapse of the infection. Refill your prescription as directed. Consult your pharmacist. It is recommended to take pyridoxine (vitamin B6) along with this drug. Ask your doctor or pharmacist about this.

Side Effects

Nausea, vomiting, abdominal pain, diarrhea, drowsiness, dizziness or metallic taste might occur. If these persist or worsen, notify your doctor promptly. Changing the time of the dosage may relieve some side effects. Unlikely but report promptly: depression. Very unlikely but report promptly: numbness or tingling of the hands and feet, seizures, shakiness, hallucinations, vision problems, yellowing of the eyes or skin, rash, mouth sores, sun sensitivity ("sunburn"), unusual bruising. Diabetics should monitor more closely for low blood sugar symptoms. If you notice other effects not listed above, contact your doctor or pharmacist.


Before taking this drug, tell your doctor your medical history, including: any allergies (especially drug allergies), liver disease, diabetes. Limit alcohol intake since alcohol can increase the drowsiness effect of this medication and also affect your liver. Use caution when performing activities requiring alertness. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known whether this drug is excreted into human milk. Consult your doctor before breast-feeding.

Drug Interactions

Tell your doctor of all nonprescription and prescription medication you may use, especially cycloserine and isoniazid. These drugs may be used with caution in tuberculosis patients when clearly necessary for combination treatment. Medications that can increase the drowsiness effect of this drug include: sedatives, tranquilizers, drugs for sleep, narcotic pain relievers, psychiatric medications (e.g., chlorpromazine), certain antidepressants (e.g., amitriptyline), certain antihistamines (e.g., diphenhydramine), muscle relaxants, anti- seizure medications. Do not start or stop any medicine without doctor or pharmacist approval.


If overdose is suspected, contact your local poison control center or emergency room immediately.


This medication has been prescribed for your current condition only. Do not use it later for another infection or give it to others. A different medication may be needed in those cases.

Missed Dose

If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.


Store at room temperature at approximately 77 degrees F (25 degrees C) away from light and moisture.

Medical Alert

Your condition can cause complications in a medical emergency. For enrollment information call MedicAlert at 1-800-854-1166 (USA), or 1-800-668-1507 (Canada).