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Ethacrynic acid oral

Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.


(eth-uh-KRIN-ick acid)


WARNING: This drug is a strong "water pill" (diuretic). Using too much of this drug can lead to serious water and mineral loss. Therefore, it is important you be monitored by your doctor. Promptly notify your doctor if you become very thirsty, have a dry mouth, become confused, or develop muscle cramps/weakness.


Ethacrynic acid is a "water pill" (diuretic) that is used to decrease the amount of water in the body by increasing urination. It is used to decrease body fluid and swelling of the hands or feet (edema), and for high blood pressure.

How To Use

Take as directed with food or milk if this drug causes stomach upset. If this medication is used in the late afternoon or evening, you may need to urinate during the night. Consult your doctor regarding your dosing schedule.

Side Effects

This drug may cause dizziness and lightheadedness especially during the first few days as your body adjusts to it. Rise slowly from a seated or lying position. Blurred vision, loss of appetite, itching, stomach upset, headache and weakness may also occur during initial therapy as your body adjusts to the medication. Inform your doctor if you develop: muscle cramps/pain, nausea, vomiting, diarrhea, hearing difficulties. This medication increases urination. Expect this effect. If you notice other effects not listed above, contact your doctor or pharmacist.


Before using this drug, tell your doctor your medical history especially of: kidney problems, unusual decrease in urine output, liver disease, any drug allergies. This drug can reduce the potassium levels in your blood. A potassium supplement may be prescribed by your doctor. Before using this drug, tell your doctor if you are pregnant. It is not known if this drug is excreted into breast milk. Consult your doctor before breast-feeding.

Drug Interactions

Tell your doctor of all prescription and nonprescription medicines you use, especially of: lithium, warfarin, aminoglycoside antibiotics (e.g., gentamicin, tobramycin), NSAIDs (e.g., indomethacin, naproxen), high blood pressure medications, ginseng. Do not start or stop any medicine without doctor or pharmacist approval.


If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include dry mouth, dizziness, excessive urination followed by a decrease in amount of urine, muscle cramps, weakness, and weak or irregular heartbeat.


Do not share this medication with others.

Missed Dose

If you miss a dose, take as soon as remembered; do not take if it is almost time for the next dose, instead, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.


Store in a tightly closed container at room temperature (77 degrees F; 25 degrees C). Brief storage between 59-86 degrees F (15 - 30 C) is permitted. Do not freeze. Do not store in the bathroom.

Medical Alert

Your condition can cause complications in a medical emergency. For enrollment information call MedicAlert at 1-800-854-1166 (USA), or 1-800-668-1507 (Canada).