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Erythrityl tetranitrate oral

Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.


(eh-RITH-rih-till teh-truh-NYE-trate)


This medication relaxes blood vessels, which improves blood flow to the heart. Erythrityl tetranitrate is used to prevent chest pain (angina). It is NOT for treating an angina attack that is already happening.

How To Use

This tablet can be placed under the tongue or swallowed. If you are placing the tablet under the tongue, allow it to dissolve completely for faster results. The drug is absorbed directly through the lining of the mouth. Take exactly as prescribed. To be effective in preventing chest pain, you must continue taking this drug even if you feel well. Do not stop taking this drug suddenly without consulting your doctor. Some conditions may become worse when the drug is suddenly stopped. Your dose may need to be gradually decreased. Notify your doctor if the medication does not appear to be as effective. Do not increase your dose or take it more often than prescribed without consulting your doctor.

Side Effects

Headache, dizziness, flushing, rapid heartbeat or restlessness may occur as your body adjusts to the medication. If they persist or become bothersome, inform your doctor. To prevent dizziness and lightheadedness when rising from a seated or lying position, get up slowly. Notify your doctor if you experience: blurred vision, dry mouth, skin rash, nausea. Headache is often a sign the medication is working. Treat headaches with an aspirin or non-aspirin pain reliever as recommended by your doctor. If the headaches continue or become severe, notify your doctor. If you notice other effects not listed above, contact your doctor or pharmacist.


Use caution engaging in activities that require alertness if this medication make you dizzy or drowsy. Hot weather may intensify the dizziness caused by this drug. Take extra care in hot weather. Avoid alcoholic beverages which can lead to dizziness and fainting. Do not smoke. This medication should be used during pregnancy only if it is clearly needed. Discuss the risks and benefits with your doctor. It is not known if this medication appears in breast milk. Consult your doctor before breast-feeding.

Drug Interactions

Tell your doctor of all medications you may use including prescription and nonprescription drugs, especially if you use: drugs for high blood pressure, certain migraine drugs (ergot alkaloids), sildenafil, high doses of aspirin. Do not start or stop any medicine without doctor or pharmacist approval.


If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include a persistent, throbbing headache; dizziness; confusion; weakness; sweating; changes in heart rate; changes in vision; flushing; nausea; and vomiting.


Some persons may develop a tolerance to the effects of this medication over time. Notify your doctor if the medication appears to be losing its effectiveness or if the chest pain continues while taking this drug.

Missed Dose

If you miss a dose, take as soon as remembered; do not take if it is almost time for the next dose, instead, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.


Store this medication away from heat or flame. Always keep this medication in its original container. Keep container closed tightly to avoid moisture.

Medical Alert

Your condition can cause complications in a medical emergency. For enrollment information call MedicAlert at 1-800-854-1166 (USA), or 1-800-668-1507 (Canada).