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Doxercalciferol oral

Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.





Doxercalciferol is used to treat persons on kidney dialysis (e.g., chronic renal disease) who have high levels of parathyroid hormone (secondary hyperparathyroidism). Parathyroid hormone helps to maintain your body's normal calcium levels; too much of this hormone can cause other health problems (e.g., weak bones, heart arrhythmias).

How To Use

Take this medication by mouth usually 3 times a week during dialysis; or as directed by your doctor. The dosage is based on your medical condition and response to therapy. Take this medication exactly as prescribed. Your dosage may need to be adjusted or stopped temporarily based on laboratory test results (e.g., PTH levels).

Side Effects

Headache, nausea, vomiting, itching, unusual tiredness, or upset stomach may occur. If any of these effects persist or worsen, notify your doctor promptly. Tell your doctor immediately if any of these serious side effects occur: swelling, constipation, unusual weight gain or weight loss, open sores (abscess), trouble breathing, joint pain, trouble sleeping, unusually slow heartbeat, dizziness. Tell your doctor immediately if any of these unlikely but serious side effects occur: bone pain, muscle pain, change in amount of urine, increased thirst, loss of appetite, metallic taste, severe stomach pain. If you notice other effects not listed above, contact your doctor or pharmacist.


Tell your doctor your medical history, especially of: liver problems, problems with high calcium blood levels (hypercalcemia) or high phosphate blood levels (hyperphosphatemia), any allergies (especially to vitamin D products). Tell your doctor if you are pregnant before using this medication. It is not known if this medication passes into breast milk. Consult your doctor before breast-feeding.

Drug Interactions

Tell your doctor of all prescription and nonprescription medication you may use, especially: calcium supplements (e.g., calcium carbonate, calcium citrate), phosphorus supplements (e.g., sodium or potassium phosphate), certain antacids (e.g., calcium or magnesium-containing antacids), vitamin D containing products, cholestyramine, mineral oil, glutethimide, phenobarbital, phenytoin, rifampin. Do not start or stop any medicine without doctor or pharmacist approval.


If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include: metal taste in the mouth, irregular heartbeat, seizures, severe mental/mood changes.


Do not share this medication with others. Laboratory and/or medical tests (e.g., PTH, calcium, magnesium, phosphorus) will be performed to monitor your progress.

Missed Dose

If you miss a dose, contact your doctor or pharmacist to establish a new dosing schedule.


Store at room temperature between 68 and 77 degrees F (20 and 25 degrees C) away from light and moisture.