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Digoxin injection

Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.





This medication is used to treat heart problems, including irregular heartbeat or congestive heart failure.

How To Use

This medication is given by injection into a vein(IV) or (infrequently) into a muscle (IM). The dosage is variable, depending on the diseases involved, the person's age, kidney function among other factors. A larger initial dose may be given (loading dose) followed by once a day doses until oral medication can be used in adults. In newborns, the dosage is variable. Beyond the newborn stage, children's doses are larger than adult doses per kilogram of weight up to age 10. A child over 10 years of age usually receives an adult dose, adjusted for body weight.

Side Effects

Report promptly any loss of appetite, irregular heartbeat/palpitations, drowsiness, nausea, diarrhea or constipation, abdominal pain, vomiting, headache, fatigue, muscle weakness or vision changes. Unlikely but report promptly: dizziness, fainting, mood changes, confusion, mental or emotional changes. Very unlikely but report promptly: black stool, seizures. Notify your doctor immediately in the unlikely event an allergic reaction occurs. Symptoms of an allergic reaction include: difficulty breathing, skin rash, itching. If you notice other effects not listed above, contact your doctor or pharmacist.


Before using this drug, tell your doctor your medical history, including: allergies (especially drug allergies), heart problems, lung or kidney diseases, high blood pressure, low thyroid function (hypothyroid), low potassium levels. Limit alcohol intake (e.g., certain liquid medications containing alcohol) since the side effects of this medication may be increased by alcohol. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. This drug is excreted into breast milk. Consult your doctor before breast-feeding. Caution is advised when this drug is used in the elderly.

Drug Interactions

Tell your doctor of all nonprescription and prescription medication you may use, especially: water pills (diuretics), amphotericin, acarbose, corticosteroids (e.g., prednisone), corticotropin, edetate, laxatives, sodium polystyrene sulfonate (Kayexalate), glucagon, calcium (IV), quinidine, procainamide, propranolol, amiodarone, propafenone, certain calcium channel blockers (e.g., verapamil, diltiazem), itraconazole, indomethacin, succinylcholine. Also report the use of drugs that make you drowsy, such as: tranquilizers, narcotic pain relievers (e.g., codeine), sleeping pills, sedatives, anti-anxiety medicines, certain antihistamines, (e.g., diphenhydramine), muscle relaxants, anti-seizure drugs, St John's wort. Do not start or stop any medicine without doctor or pharmacist approval.


If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include changes in vision, loss of appetite, nausea, vomiting, diarrhea, dizziness, weakness, and irregular heartbeat.


Heart monitoring and blood tests are performed during treatment with digoxin injection.

Missed Dose

If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and consult your doctor or pharmacist for a new dosing plan.


Store at room temperature between 59 and 77 degrees F (15-25 degrees C) away from light and moisture.

Medical Alert

Your condition can cause complications in a medical emergency. For enrollment information call MedicAlert at 1-800-854-1166 (USA), or 1-800-668-1507 (Canada).