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Dexamethasone sod phosphate injection

Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.



COMMON BRAND NAME(S): Adrenocot, CPC-Cort-D, Decadron Phosphate, Decaject-10, Solurex


Dexamethasone is a corticosteroid that reduces swelling and inflammation. It is used to treat a variety of disorders such as skin diseases (e.g., dermatitis, keloids), allergic conditions, breathing problems, cancer (e.g., leukemias, lymphomas), blood disorders (e.g., anemia), digestive problems (e.g., colitis, enteritis), or arthritis.

How To Use

Inject this medication into a vein (IV), into a muscle (IM), into a joint (intra-articular), or into a skin wound as directed by your doctor. The dosage is based on your medical condition and response to therapy. Do not stop using this medication without consulting your doctor. Some conditions may become worse when the drug is abruptly stopped. Your dose may need to be gradually decreased before stopping treatment. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Learn how to store and discard needles and medical supplies safely. Consult your pharmacist.

Side Effects

Nausea, dizziness, increased appetite, weight gain, weakness, sleep problems, or pain/redness/swelling at the injection site may occur. If any of these effects persist or worsen, notify your doctor promptly. Tell your doctor immediately if any of these serious side effects occur: swelling of the face/ankles/feet, muscle pain and weakness, severe headache, trouble breathing, rash, wounds that won't heal. Tell your doctor immediately if any of these unlikely but serious side effects occur: severe stomach pain, bloody or black stools, mental/mood changes, seizures, increased thirst, increased urination, blurred vision, persistent sore throat or fever. An allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include: rash, itching, swelling, severe dizziness, trouble breathing. Contact your doctor if you experience any of the following signs of low steroid levels: unusual weakness, weight loss, nausea, vomiting, fainting or dizziness. If you notice other effects not listed above, contact your doctor or pharmacist.


Tell your doctor your medical history, especially of: liver or kidney disease, heart problems, stomach or intestinal problems (e.g., ulcers), high blood pressure, brittle bones (osteoporosis), seizures, blood clots (thromboembolism), bleeding disorders (e.g., hemophilia), recent infections, mental disorders (e.g., depression, schizophrenia), glandular diseases (e.g., thyroid, adrenal), diabetes, myasthenia gravis, herpes infections, eye problems, any allergies. When used for extended periods and/or used in children, this drug can suppress your immune system function. Tell your doctor if you experience any injuries and/or signs of infection (e.g., fever, sore throat, muscle aches, pain during urination) during treatment and within 12 months after treatment with this drug. Consult your doctor or pharmacist for more details. Avoid contact with people currently infected with the chicken pox or measles. Consult your doctor immediately if you think you have been exposed to the chicken pox or measles virus. Do not have vaccinations/immunizations/skin tests while you are taking this drug unless directed by your doctor. If you have diabetes, this drug may increase your blood sugar levels. Test your blood for sugar (glucose) frequently and contact your doctor if your levels are high; your dose of diabetes medicine and your diet may need to be changed or adjusted. A preservative (benzyl alcohol) which may be found in this product or in the liquid used to mix this product (diluent) can infrequently cause serious problems (sometimes death) if given by injection to an infant during the first months of life (neonatal period). The risk is greater with lower birth weight infants and is greater with increased amounts of benzyl alcohol. Symptoms include sudden gasping, low blood pressure, or a very slow heartbeat. Report these symptoms to the doctor immediately should they occur. If possible, a preservative-free product should be used when treating neonates. Caution is advised when using this drug in children because it can affect their growth (suppress growth hormone). This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. This medication passes into breast milk and has had undesirable effects on nursing infants. Consult your doctor before breast- feeding.

Drug Interactions

Tell your doctor of all prescription and nonprescription medication you may use, especially: aspirin, certain anti-seizure drugs (e.g., phenobarbital, phenytoin), ephedrine, rifampin, "blood thinners" (e.g., coumadin), "water pills" (diuretics such as furosemide or hydrochlorothiazide). Do not start or stop any medicine without doctor or pharmacist approval.


If overdose is suspected, contact your local poison control center or emergency room immediately.


Do not share this medication with others. Inform all your doctors you use, or have used, this medication. Laboratory and/or medical tests may be performed to monitor your progress.

Missed Dose

If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.


Store at room temperature between 36 and 86 degrees F (2 to 30 degrees C) away from light and moisture.

Medical Alert

Your condition can cause complications in a medical emergency. For enrollment information call MedicAlert at 1-800-854-1166 (USA), or 1-800-668-1507 (Canada).