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Darbepoetin alfa in albumn sol injection
DARBEPOETIN ALFA - INJECTABLE

Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.

DARBEPOETIN ALFA - INJECTABLE

(DAR-boh-poh-EE-tin AL-fuh)

COMMON BRAND NAME(S): Aranesp

Uses

Darbepoetin alfa is used to treat low red blood cell counts (anemia) either in people with long-term kidney failure (chronic renal failure) or in people with certain types of cancer (non-myeloid) who are receiving chemotherapy. It works by stimulating the bone marrow to make more red blood cells.

How To Use

Learn how to prepare and inject the drug and review the darbepoetin alfa Patient Information Booklet. If any of the information is unclear, consult your doctor or pharmacist. Do not shake the vial or syringe and do not mix this drug with IV solutions or other injectable drugs. Consult your pharmacist. Inject this medication into a vein (IV) or under the skin (SC) usually once weekly; or as directed by your doctor. The dosage is based on your weight, medical condition, and response to therapy. Use this medication exactly as prescribed. Do not increase your dose, use it more frequently, or use it for a longer period of time than prescribed because doing so may increase your chance for serious side effects. It may take up to 4 weeks before the full benefit of this drug takes effect. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Learn how to store and discard needles and medical supplies safely. Consult your pharmacist.

Side Effects

Headache, diarrhea, nausea, vomiting, cough, or constipation may occur. If any of these effects persist or worsen, notify your doctor. Tell your doctor immediately if any of these serious side effects occur: pain/irritation/redness/bruising at the injection site, other pain (e.g., muscle, joint, back, stomach, or chest pain), unusual tiredness/weakness, swelling of the arms/legs. Tell your doctor immediately if any of these unlikely but serious side effects occur: flu-like symptoms (e.g., fever, chills, sore throat, muscle aches), blurred vision, irregular heartbeat, severe chest pain, shortness of breath, pain in the legs or groin. Tell your doctor immediately if any of these highly unlikely but very serious side effects occur: seizures, one-sided weakness, slurred speech, confusion. An allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.

Precautions

This medication is not recommended for use if you have the following medical conditions: uncontrolled high blood pressure. Tell your doctor your medical history, especially of: heart problems, other blood disorders (e.g., sickle cell anemia, porphyria), vitamin deficiencies (e.g., B-12, folate), seizures, high blood pressure (treated or controlled), recent infections or injury, cancer, inflammatory conditions (e.g., bowel disease, rheumatoid arthritis), any allergies. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known if this drug passes into breast milk. Consult your doctor before breast-feeding.

Drug Interactions

Tell your doctor of all prescription and nonprescription medication you may use, especially: other blood- related products (e.g., erythropoietin alfa). Do not start or stop any medicine without doctor or pharmacist approval.

Overdose

If overdose is suspected, contact your local poison control center or emergency room immediately.

Notes

Do not share this medication with others. Laboratory and/or medical tests (e.g., hemoglobin, blood pressure) may be performed to monitor your progress. It is important to follow recommended dietary guidelines while using this medication. Eating foods rich in iron may be recommended (e.g., raisins, figs, meats, eggs, vegetables).

Missed Dose

If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

Storage

Store refrigerated between 36 and 46 degrees F (2 and 8 degrees C) away from light. Do not freeze or shake the vials or syringes. Discard any unused portion of the vial or syringe.

Medical Alert

Your condition can cause complications in a medical emergency. For enrollment information call MedicAlert at 1-800-854-1166 (USA), or 1-800-668-1507 (Canada).