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Daptomycin intraven.
DAPTOMYCIN- INJECTION

Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.

DAPTOMYCIN- INJECTION

(DAP-toe-mye-sin)

COMMON BRAND NAME(S): Cubicin

Uses

This medication is a cyclic lipopeptide antibiotic used to treat serious bacterial skin infections. This drug will only treat infections caused by certain bacteria and will not work for infections caused by viruses. This drug should not be used to treat pneumonia. If used to treat pneumonia, you may experience severe side effects (especially heart and breathing problems). Consult your doctor for more details.

How To Use

This medication is given by vein intravenously (IV) usually once daily. If you have severe kidney disease or are on kidney dialysis, you should only receive this medication every other day (i.e., every 48 hours). Usually this drug is used for two weeks; or use as directed by your doctor. Follow all instructions for proper mixing and dilution with the correct IV fluids. If you have any questions about the mixing or use of this medication, ask your pharmacist. Before using, check this product visually for particles. If present, do not use the liquid. Antibiotics work best when the amount of medicine in your body is kept at a constant level. Therefore, take this drug at evenly spaced intervals. Continue to take this medication until the full-prescribed amount is finished even if symptoms disappear after a few days. Stopping the medication too early may allow bacteria to continue to grow, which may result in a relapse of the infection. Inform your doctor if your condition does not improve in one week. Learn how to store and discard needles and medical supplies safely. Consult your pharmacist.

Side Effects

Nausea, vomiting, constipation, diarrhea, headache, dizziness, trouble sleeping, anxiety, or pain/redness/swelling at the injection site may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Tell your doctor immediately if any of these unlikely but serious side effects occur: muscle pain/cramps/weakness, numbness or tingling of hands or feet, unusual tiredness or weakness, change in amount of urine, chest pain, swelling, shakiness, sweating, increased thirst, blurred vision. Tell your doctor immediately if any of these highly unlikely but very serious side effects occur: unusual bleeding or bruising, irregular heartbeat, yellowing of the skin or eyes, dark urine. This medication may rarely cause a severe intestinal condition (pseudomembranous colitis) due to a resistant bacteria. This condition may occur weeks after treatment has stopped. Do not use anti-diarrhea products or narcotic pain medications if you have the following symptoms because these products may make them worse. Tell your doctor immediately if you develop: persistent diarrhea, abdominal or stomach pain/cramping, blood/mucus in your stool. Use of this medication for prolonged or repeated periods may result in oral thrush or a new vaginal yeast infection (oral or vaginal fungal infection). Contact your doctor if you notice white patches in your mouth, a change in vaginal discharge or other new symptoms. A serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching, severe swelling, severe dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.

Precautions

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: severe diarrhea (pseudomembranous colitis). Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease or kidney dialysis, muscle problems (e.g., myopathy), any allergies. This drug may make you dizzy; use caution engaging in activities requiring alertness such as driving or using machinery. Limit alcoholic beverages. Caution is advised when using this drug in the elderly because they may be more sensitive to the effects of the drug. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding.

Drug Interactions

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: aminoglycosides (e.g., tobramycin), "blood thinners" (e.g., warfarin), "statin" drugs for cholesterol (e.g., simvastatin, lovastatin), live vaccines. Do not start or stop any medicine without doctor or pharmacist approval.

Overdose

If overdose is suspected, contact your local poison control center or emergency room immediately.

Notes

Do not share this medication with others. This medication has been prescribed for your current condition only. Do not use it later for another infection unless told to do so by your doctor. A different medication may be necessary in those cases. Laboratory and/or medical tests (e.g., CPK levels) should be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.

Missed Dose

If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

Storage

Refrigerate between 36 and 46 degrees F (2-8 degrees C). This medication must be used immediately after mixing. The mixed drug may be stored for up to 12 hours at room temperature or 48 hours in the refrigerator. If not used within this time, throw out the medicine and mix a brand new dose. Keep all medicines away from children and pets.