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Danaparoid sodium,porcine subcutane.

Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.




WARNING: Tell your doctor you are using this medication before undergoing any procedure involving spinal puncture/anesthesia. Using this medication before these procedures has caused major bruising or bleeding (epidural or spinal hematoma) inside your body. This may leave you paralyzed, maybe permanently. Tell your doctor immediately if you have any of these serious side effects: tingling, weakness, numbness, difficulty urinating or pain. This risk is increased when you use other "blood thinning" medications (e.g., aspirin, clopidogrel, warfarin), NSAIDs (e.g., ibuprofen, naproxen), or when certain medication delivery devices (indwelling epidural catheters) are used. You will be monitored closely while you are on this medication.


This medication is a "blood thinner" which helps prevent formation of blood clots. It is used after hip replacement surgery.



This drug may also be used to treat actual blood clots in certain circumstances.

How To Use

This medication is given by injection under the skin (subcutaneously) by a health care professional usually twice daily following surgery. Injection sites will be rotated to limit irritation. Therapy with this drug may be continued for 7 to 14 days or until the risk of blood clot formation is limited. This drug should not be injected into a muscle (IM).

Side Effects

Nausea, constipation, pain, redness or irritation at the injection site, headache, weakness or dizziness may occur. If these persist or worsen, notify your doctor promptly. Report promptly: unusual bleeding or bruising, black stools, fever. Unlikely but report promptly: swelling of the hands or feet, trouble sleeping, joint pains, urinary problems. If you have had a spinal procedure along with this drug, promptly report: weakness, numbness, pain. In the unlikely event you have an allergic reaction to this drug, seek immediate medical attention. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.


Tell your doctor your medical history, especially of: allergies (especially drug or pork allergies), bleeding disorders, strokes, kidney problems, severe high blood pressure, heart infections, stomach or intestinal ulcers, recent nervous system or eye surgery. Tell your doctor if you are pregnant before using this medication. It is not known if this drug is excreted into breast milk. Consult your doctor before breast-feeding.

Drug Interactions

Tell your doctor of all nonprescription and prescription medication you may use, especially of: other blood thinners (e.g., warfarin, heparin), aspirin, NSAIDs (e.g., ibuprofen, naproxen). Do not start or stop any medicine without doctor or pharmacist approval.


If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include excessive bleeding and bruising, slowed breathing, exhaustion, and muscle twitching.


Laboratory tests will be done periodically while using this medication to monitor its effects and to prevent side effects. Do not share this medication with others.

Missed Dose

Try to use each dose at the scheduled time. If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.


Store the glass container (ampule) at temperatures between 36 and 86 degrees F (2-30 degrees C) away from light and moisture. Refrigerate the syringe form between 36 and 46 degrees F (2-8 degrees C). Do not freeze these products.