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Cocaine HCl topical

Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.




Cocaine is used as a local anesthetic to temporarily numb areas of the mouth, nose, and throat (mucous membranes).

How To Use

This medication is applied directly to the inside of the mouth, nose, or throat. The dosage depends on your condition and response to the drug. Do not use by vein (IV) or in the eye. Follow all instructions for proper use. Consult your pharmacist for details. When used for extended periods, this medication may not work as well and may require different dosing. Consult the doctor if the medication is not working well. Use this medication exactly as prescribed. Do not increase your dose, take it more frequently, or use for a longer period of time than prescribed because this drug can be habit-forming. Also, if used for a longer period of time, do not stop using this drug without your doctor's approval.

Side Effects

Nausea, nervousness, and restlessness may occur. If this effect persists or worsens, notify your doctor promptly. Tell your doctor immediately if any of these serious side effects occur: mental/mood changes, loss of smell or taste. Tell your doctor immediately if any of these unlikely but serious side effects occur: trouble breathing, chills, fever, unusually fast or slow heartbeat, chest pain, tremors, fainting. Tell your doctor immediately if any of these highly unlikely but very serious side effects occur: seizures, vision problems (e.g., blurred vision, hallucinations, sensitivity to light). If you notice other effects not listed above, contact your doctor or pharmacist.


Tell your doctor your medical history, especially of: high blood pressure, heart disease, thyroid problems (e.g., hyperthyroid), seizures, infections, sores or trauma in the area of the application site (e.g., mouth, nose, throat), any allergies. This medication should be used with caution in children because they may be more sensitive to side effects (e.g., mental/ mood changes). This medication should be used with caution in the elderly because they may be more sensitive to side effects (e.g., mental/ mood changes). This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. This drug is excreted into breast milk. Because of the potential risk to the infant, breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding.

Drug Interactions

Tell your doctor of all prescription and nonprescription medication you may use, especially: stimulant-type drugs (e.g., catecholamines such as norepinephrine or epinephrine; ephedrine, pseudoephedrine, or amphetamines), beta-blockers (e.g., nadolol, propranolol), MAO inhibitors (e.g., furazolidone, linezolid, phenelzine, selegiline, tranylcypromine). Do not start or stop any medicine without doctor or pharmacist approval.


If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include: vomiting, stomach/abdominal pain, severe headache, irregular breathing, seizures, fainting.


Do not share this medication with others; it is against the law.

Missed Dose

Not applicable.


Store at room temperature between 59 and 86 degrees F (15 to 30 degrees C) away from light and moisture.