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Clomipramine HCl oral

Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.





This medication is used in the treatment of Obsessive Compulsive Disorders (OCD). It may take 2 to 3 weeks before the full effects of this medication are noticed.

How To Use

Take this medication exactly as prescribed. When first taking this medication, your doctor may increase your dose gradually to determine the best effective dose. This medication may be taken with food to prevent stomach upset. Do not stop taking this medication without your doctor's approval. Nausea, headache or fatigue can occur if the drug is suddenly stopped.

Side Effects

This medication may cause drowsiness, dizziness, increased sun sensitivity or blurred vision. Use caution performing tasks that require alertness. This medication may initially cause dizziness and lightheadedness when rising too quickly from a sitting or lying position. Change positions and get out of bed slowly. Other side effects may include heartburn, weight gain, dry mouth, strange taste in mouth, anxiety, restlessness or sweating. These effects should subside as your body adjusts to the medication. Inform your doctor if they continue or become bothersome. Notify your doctor if you develop: chest pain, a rapid heart rate, difficulty urinating, nightmares, ringing in the ears, excessive sedation, uncoordinated movements, fainting. Males may experience sexual dysfunction while taking this medication. In the unlikely event you have an allergic reaction to this drug, seek medical attention immediately. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.


Before using this drug tell your doctor your medical history, especially of: glaucoma, prostate problems, decreased urine output, thyroid disease, breathing problems, seizure problems, alcohol use, heart disease, mental/emotional problems, liver or kidney disease, drug allergies. This medication can increase sensitivity to sunlight. Avoid prolonged sun exposure. Wear a sunscreen and protective clothing. Limit alcohol while using this drug to avoid excessive drowsiness. Caution is advised when using this drug in the elderly, because they may be more sensitive to the effects of the drug (e.g., confusion may occur or worsen). This drug should be used during pregnancy only if clearly needed. Discuss the risks and benefits with your doctor. This drug is excreted into breast milk. The effects on the infant are not known at this time. Consult your doctor before breast-feeding.

Drug Interactions

Inform your doctor about what drugs you take especially of: drugs used to treat an over-active thyroid, MAO inhibitors (e.g., furazolidone, linezolid, phenelzine, selegiline, tranylcypromine), other tranquilizers, medicines that make you excited, high blood pressure drugs, narcotic pain medications (e.g., codeine), SSRI antidepressants (e.g., fluoxetine, fluvoxamine), other drugs you use (both prescription and non- prescription), St John's wort. Do not start or stop any medicine without doctor or pharmacist approval.


If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include flushing, fast or irregular heartbeat, dry mouth, drowsiness, confusion, agitation, enlarged pupils, seizures, and loss of consciousness.


Taking this medication at bedtime may help minimize side effects such as day time sleepiness. Talk to your doctor about this.

Missed Dose

If you miss a dose, take as soon as remembered; do not take if it is almost time for the next dose, instead, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.


Store at room temperature away from sunlight and moisture.