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Cladribine intraven.
CLADRIBINE - INJECTION

Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.

CLADRIBINE - INJECTION

(KLAD-rib-een)

COMMON BRAND NAME(S): Leustatin

WARNING: Cladribine can be expected to suppress bone marrow function leaving patients susceptible to infection. At high doses, cladribine can harm the nervous system or kidneys. Notify your doctor immediately if you develop signs of infection, kidney problems or nervous system problems such as persistent sore throat or fever; change in amount of urine; or tingling or numbness sensations in the hands and feet.

Uses

Cladribine is an anticancer medication used to treat certain leukemias.

OTHER

Uses

This medication may also be used to treat tumors (lymphomas).

How To Use

This medication is given by continuous infusion into a vein usually for 7 consecutive days. Doses may be delayed or discontinued based on response.

Side Effects

Headache, nausea, decreased appetite, fatigue, dizziness, cough, sweating, or irritation at the injection site may occur the first several days as your body adjusts to the medication. If any of these effects continue or become bothersome, inform your doctor. Tell your doctor immediately if any of these serious side effects occur: fever, chills, skin rash, rapid heart rate, breathing trouble, muscle weakness, tingling in the hands or feet, pain/redness/swelling at the injection site. This medication can cause blood disorders. Laboratory tests will be done to monitor for this and other possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

Precautions

Tell your doctor if you have: pre-existing kidney disease, muscle disease, liver disease, bone marrow disease, blood disorders, infection, any allergies. Cladribine is not recommended for use during pregnancy. Consult your doctor before using this drug. Avoid pregnancy while using this medication. Use effective birth control. It is not known if this medication appears in breast milk. Consult your doctor before breast-feeding.

Drug Interactions

Tell your doctor of any over-the-counter or prescription medication you may take including: corticosteroids, other anticancer medications. Do not start or stop any medicine without doctor or pharmacist approval.

Overdose

If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include tingling or numbness in the arms or legs.

Notes

This medication is usually first administered in a hospital setting where your condition can be monitored closely. Laboratory and/or medical tests (e.g., blood) will be performed to monitor your progress.

Missed Dose

It is important to receive this medication as directed. However, doses may be stopped or held depending on your condition. Discuss the dosing schedule with your doctor. Do not "double-up" the dose to catch up.

Storage

Store in the refrigerator and protect from light as directed. Check the expiration date and discard any unused medication after that time.