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Chloramphenicol oral

Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.



WARNING: Rarely, this medication has caused serious, sometimes fatal blood disorders (e.g., aplastic anemia, hypoplastic anemia). Do not use chloramphenicol if safer, effective medications can be used. Do not use this medication to treat or prevent simple infections such as a cold or the flu. Immediately notify your doctor if you have easy bruising or bleeding, persistent sore throat or fever, or unusual fatigue.


Chloramphenicol is an antibiotic used to treat a variety of bacterial infections.

How To Use

This medication is best taken on an empty stomach 1 hour before or 2 hours after meals. It may be taken with food or milk if stomach upset occurs. The liquid suspension form of this medicine must be shaken well before using. Store in the refrigerator. Check the expiration date and discard any unused portion after 14 days because the drug loses potency. Antibiotics work best when the amount of medicine in your body is kept at a constant level. Do this by taking the medication at evenly spaced intervals throughout the day and night. Continue to take this medication until the full prescribed amount is finished even if symptoms disappear after a few days. Stopping the medication too early may allow bacteria to continue to grow resulting in a relapse of the infection.

Side Effects

This medication may cause stomach upset, diarrhea, headache, nausea, and vomiting which should disappear in a few days as your body adjusts to the medication. If these symptoms persist or become severe, inform your doctor. Notify your doctor immediately if you experience: fever, fatigue, sore throat, unusual bleeding or bruising, abdominal pain, bloating, vision changes or eye pain, tingling of the hands or feet. In the unlikely event you have an allergic reaction to this drug, seek medical attention immediately. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.


Before using this drug, tell your doctor your medical history especially of: liver disease, kidney disease, G6PD deficiency, porphyria, any drug allergies. Use extreme caution when giving this drug to children less than 2 years old. This drug should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. This drug is excreted into breast milk. It is not known if it is safe to breast-feed while using this drug. Consult your doctor before breast-feeding.

Drug Interactions

Tell your doctor of all prescription and nonprescription drugs you may use, especially of: diabetes medicine, warfarin, phenytoin, phenobarbital, rifampin, other antibiotics, vitamin B12, iron, folic acid. This drug may interfere with the effectiveness of birth control pills. Discuss using other methods of birth control with your doctor. Do not start or stop any medicine without doctor or pharmacist approval.


If overdose is suspected, contact your local poison control center or emergency room immediately.


This medication has been prescribed for your current condition only. Do not use it later for another infection or give it to someone else. A different medication may be necessary.

Missed Dose

If you miss a dose, take as soon as remembered. If, however, it is almost time for the next dose and the dose is 2 daily, take the missed dose and the next dose 6 hours apart. If the dose is 3 daily, take the missed dose and the next dose 2 to 4 hours apart. Then resume usual dosing schedule. Do not "double-up" the dose to catch up.


Store at room temperature away from moisture and sunlight. Follow label warnings about whether or not to refrigerate liquid forms. Do not freeze. Do not store in bathroom.