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Cascara sagrada and Magnesium hydroxide oral

Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.


(mag-NEE-zee-um hi-DROX-ide w/kass-CARE-uh)

COMMON BRAND NAME(S): Milk of Magnesia W/Cascara


This medication is used for the short-term treatment of constipation or to empty the bowel before bowel or stomach procedures.

How To Use

Take by mouth, generally once daily, as needed or as directed by your doctor. Do not exceed the maximum recommended dose. Consult your doctor or pharmacist. Do not use this medication for more than 7 days unless directed by your doctor. Do not use this medication if you have had a change in bowel habits for longer than 2 weeks or if there is blood in your stool. Instead, consult your doctor or pharmacist. Long-term use of laxatives may lead to laxative dependence, chronic constipation, loss of normal bowel function and damage to the bowel. Overuse of laxatives may cause persistent diarrhea, dehydration and body mineral problems. The magnesium hydroxide in this product may interfere with the absorption of other drugs you may take. Take this product at least 2 hours before or 2 hours after you take these medications: tetracycline antibiotics (e.g., doxycycline, tetracycline); quinolone antibiotics (e.g., ciprofloxacin); azole antifungal drugs (e.g., ketoconazole); seizure drugs (e.g., phenytoin); dexamethasone, indomethacin, digoxin, iron/multivitamin supplements or sodium polystyrene sulfonate. Consult your pharmacist.

Side Effects

Stomach pain, nausea or diarrhea may occur. If these effects persist or worsen, notify your doctor. Unlikely but report promptly: muscle twitching or cramping, muscle weakness, decrease or absence of bowel movements, blood in stool, mental/mood changes, dizziness. This medication may cause your urine to temporarily turn a reddish pink or brown color. This effect is harmless. If you notice other effects not listed above, contact your doctor or pharmacist.


If you have any of the following health problems, consult your doctor before using a laxative: any allergies, stomach/intestinal problems, nausea, vomiting, blood in the stool, kidney disease. This medication should be used with caution in children and is not recommended for use in those less than 6 years old, unless directed by a doctor. Children may be more likely to become dehydrated. Consult your doctor or pharmacist. This product should be used only when clearly needed during pregnancy. Discuss the benefits and risks with your doctor. The cascara in this product is excreted into breast milk. Because of the potential risk to the infant, breast-feeding while using this product is not recommended. Consult your doctor before breast-feeding.

Drug Interactions

Tell your doctor of all prescription and nonprescription medication you use, especially of: tetracycline antibiotics (e.g., doxycycline or tetracycline), azole antifungals (e.g., ketoconazole), quinolone antibiotics (e.g., ciprofloxacin), anti-seizure medications (e.g., phenytoin, valproic acid), heart heart drugs (e.g., quinidine, digoxin), sodium polystyrene sulfonate, dexamethasone, indomethacin, "blood thinners" (e.g., warfarin), iron/multivitamin supplements. Do not start or stop any medicine without doctor or pharmacist approval.


If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include severe diarrhea, nausea, or vomiting; dry gums or eyes; loss of appetite, muscle cramps, weakness, or sluggishness.


Do not share this medication with others. Proper diet, fluid intake and exercise may help prevent constipation. Consult your doctor or pharmacist.

Missed Dose

If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.


Store at room temperature between 59 and 86 degrees F (15 to 30 degrees C) away from light and moisture.