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Bivalirudin intraven.

Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.





Bivalirudin is a "blood thinner" used in patients with certain heart problems (unstable angina) during a type of heart procedure (e.g., percutaneous transluminal coronary angioplasty - PTCA). This medication helps prevent blood clots from forming during and after this type of procedure and is usually used along with aspirin.

How To Use

Follow all instructions for proper mixing and dilution with the correct IV fluids. If you have any questions regarding the use of this medication, consult your pharmacist. Give this medication by vein (IV) exactly as prescribed by the doctor. The dosage is based on the patient's weight, medical condition, and response to therapy. This medication should not be mixed with other injectable medications or used for longer than 24 hours. Consult your pharmacist. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Learn how to store and discard needles and medical supplies safely.

Side Effects

Nausea, vomiting, heartburn, pain/redness/swelling at the injection site, headache, or trouble sleeping may occur. If any of these effects persist or worsen, contact the doctor or pharmacist. Tell the doctor immediately if any of these serious side effects occur: unusual bleeding or bruising, blurred vision, dizziness, lightheadedness, pain (especially back pain, stomach/abdominal pain, or pelvic pain), mental/mood changes, persistent sore throat or fever. Tell the doctor immediately if any of these unlikely but serious side effects occur: unusually slow heartbeat, change in amount of urine, unusual tiredness or weakness. Tell the doctor immediately if any of these highly unlikely but very serious side effects occur: one-sided weakness, loss of coordination, slurred speech, confusion, trouble breathing. If you notice any other effects not listed above, contact the doctor or pharmacist.


Tell the doctor your complete medical history, especially of: kidney problems, other blood or bleeding problems (e.g., active bleeds, anemia, coagulopathy, thrombocytopenia). Tell the doctor if you are pregnant before using this medication. It is not known whether this drug passes into breast milk. Consult the doctor before breast-feeding.

Drug Interactions

Tell the doctor of all prescription and nonprescription medications used, especially: other blood thinners (heparins, warfarin, thrombolytics, or platelet inhibitors). Do not start or stop any medicine without doctor or pharmacist approval.


If overdose is suspected, stop the medication and contact the local poison control center or emergency room immediately. Symptoms of overdose may include: unusual/severe bleeding.


Laboratory and/or medical tests (e.g., blood counts) will be performed to monitor progress.

Missed Dose

If the dose is interrupted, contact the doctor to establish a new dosing schedule/rate.


Store the unmixed powder/vials at room temperature (77 degrees F or 25 degrees C) away from light and moisture. Once mixed, the vial solution is good for up to 24 hours refrigerated (between 36 and 46 degrees F or 2 and 8 degrees C). Discard any unused portion of the vial. Do not freeze. After mixing and subsequent dilution with IV fluids, this product is stable at room temperature for up to 24 hours.

Medical Alert

Your condition can cause complications in a medical emergency. For enrollment information call MedicAlert at 1-800-854-1166 (USA), or 1-800-668-1507 (Canada).