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Basiliximab intraven.
BASILIXIMAB - INJECTION

Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.

BASILIXIMAB - INJECTION

(bass-ih-LICKS-ih-mab)

COMMON BRAND NAME(S): Simulect

Uses

Basiliximab is a monoclonal antibody. It is used to prevent rejection of transplanted organs (e.g., kidney).

How To Use

Give this medication directly into a vein (IV); or use as directed by your doctor. This medication is usually given in two doses: the first dose is given within two hours prior to transplant surgery and the second dose is given four days after surgery. This medication is used in addition to other medications (e.g., cyclosporine, corticosteroids) to prevent rejection of transplanted organs. Take all medications exactly as prescribed by your doctor. If you have any questions, ask your doctor or pharmacist. Follow all instructions for proper mixing and dilution with correct IV fluids. When mixing the diluted solution, gently invert the bag to avoid foaming; do not shake. Ask your pharmacist if you have questions regarding the use of this medication. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid.

Side Effects

Nausea, stomach pain, diarrhea, constipation, headache, or mild dizziness may occur. If any of these effects persist or worsen, contact your doctor or pharmacist promptly. Tell your doctor immediately if any of these serious side effects occur: fever, cough, weakness, sores around the mouth or genitals, unusual bleeding or bruising, vision problems, mental/mood changes, pain with urination, change in the amount of urine, chest pain, irregular pulse. Tell your doctor immediately if any of these serious but very unlikely side effects occur: unusual lumps, swollen glands, night sweats, unexplained weight loss. An allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include: rash, itching, swelling, severe dizziness, unusually fast or slow heartbeat, sneezing, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.

Precautions

Tell your doctor your medical history, especially of: any allergies you have. This drug may make you dizzy. Use caution when engaging in activities requiring alertness such as driving or using machinery. Limit alcoholic beverages because they can intensify the dizziness effect of this medication. If you must stop using this drug due to an allergic reaction, never use the drug again. Consult your doctor or pharmacist for more details. If you must restart basiliximab, you have a chance of developing an allergic reaction. Know the symptoms of this allergic reaction (see side effects section). Consult your doctor or pharmacist before restarting basiliximab, and be sure you have easy access to medical care if you are restarting treatment. The use of medications that affect the immune system may lead to increased risk of infection or certain types of cancer. Notify your doctor promptly if you experience fever, weakness, swollen glands, night sweats, unusual lumps, or any new symptoms. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. Women of childbearing potential should use effective birth control before beginning therapy with this drug, during the use of this drug, and for two months after finishing therapy with this drug. Consult your doctor or pharmacist for more information. It is not known if this drug passes into breast milk. Because of the potential risk to the infant, breast-feeding while using this medication is not recommended. Consult your doctor before breast-feeding.

Drug Interactions

Tell your doctor or pharmacist of all prescription and nonprescription drugs you may use. Do not start or stop any medicine without doctor or pharmacist approval.

Overdose

If overdose is suspected contact your local poison control center or emergency room immediately.

Notes

Do not share this medication with others. Laboratory and/or medical tests may be performed to monitor for side effects and response to treatment.

Missed Dose

If you miss a dose, contact your doctor or pharmacist immediately (see Precautions section for more details).

Storage

Refrigerate vials between 36 and 46 degrees F (2 and 8 degrees C) away from light and moisture. Do not freeze. After mixing and dilution in correct IV fluids (consult your pharmacist for details), the drug is stable at refrigerator temperature for 24 hours or at room temperature for 4 hours. Discard any unused liquid.

Medical Alert

Your condition can cause complications in a medical emergency. For enrollment information call MedicAlert at 1-800-854-1166 (USA), or 1-800-668-1507 (Canada).