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Baclofen intrathec.

Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.




WARNING: Suddenly stopping this medication may result in high fever, confusion, increased awkward muscle movements, muscle stiffness, and in rare cases, death. If you experience any of the symptoms listed above seek immediate medical attention. It is important to insure that this drug is not stopped suddenly by learning how to properly use the pump, refilling the pump on time, and being aware of the pump alarms and what to do if the pump alarms. This is especially important for certain patients who are at greater risk (e.g., spinal cord injuries at T-6 or above, communication difficulties, history of withdrawal symptoms from either oral or intrathecal baclofen). Always keep your scheduled appointments for refilling this medicine. If you must miss a refill appointment, contact your doctor immediately to reschedule the appointment before you run out of drug.


This medication is used to treat muscle spasms.



This drug may also be used for the treatment of facial pain (trigeminal neuralgia), uncontrolled movements or muscle twitching (e.g., tardive dyskinesia) and rigidity (Parkinson's disease).

How To Use

This medication is injected into the spinal cord (intrathecal) as directed by your doctor. Dosage is adjusted based on your condition and response to therapy. Follow all instructions for proper dilution with the correct fluids. Consult your pharmacist. This drug product should be checked visually for particles or discoloration before use. If present, do not use the liquid. When used for extended periods, this drug may not work as well and may require different dosing. Consult your doctor if this medication is not relieving the muscle spasms sufficiently. Do not stop treatment abruptly; consult your doctor. Make sure needles and medical supplies are stored safely and disposed of properly.

Side Effects

Constipation, dizziness, drowsiness, weakness, headache, trouble sleeping; change in amount or frequency of urine; loss of appetite, change in sexual ability, or changes in pulse may occur. If these effects persist or worsen, notify your doctor. Unlikely but report promptly: fainting, pink urine, mental/mood changes. Very unlikely but report promptly: chest/leg pain, seizures, difficulty speaking, numbness/tingling, fever, vision changes, unsteadiness, swelling. In the unlikely event you have an allergic reaction to this drug, seek immediate medical attention. Symptoms of an allergic reaction include: rash, itching, swelling, severe dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.


Tell your doctor your medical history, including: any allergies, diabetes, seizures, kidney disease, strokes, stomach/intestinal ulcers, mental/mood disorders. Limit alcohol intake, as it may aggravate certain side effects of this drug. Caution is advised when performing tasks requiring alertness (e.g., driving). To avoid dizziness and lightheadedness, get up slowly when rising from a seated or lying position. Caution is advised when this drug is used in the elderly, as they may be more sensitive to the side effects of baclofen. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known whether this drug is excreted into breast milk. Because of the potential risk to the infant, breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding.

Drug Interactions

Tell your doctor of all nonprescription and prescription medication you may use, especially drugs causing drowsiness, such as: medicine for sleep, sedatives, tranquilizers, anti-anxiety drugs, narcotic pain relievers (e.g., codeine), psychiatric medicines, anti-seizure drugs, other muscle relaxants, certain antihistamines (e.g., diphenhydramine). Check all nonprescription medicine labels carefully, especially cough-and-cold preparations, since many may contain antihistamines (e.g., diphenhydramine) which can cause drowsiness. Consult your pharmacist if you have any questions. Do not start or stop any medicine without doctor or pharmacist approval.


If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include drowsiness, lightheadedness, dizziness, slow or shallow breathing, seizures, loss of muscle tone, and loss of consciousness.


Do not share this medication with others.

Missed Dose

If you are using a pump to receive this medication, always keep your scheduled refill visits. If you must miss an appointment, contact your doctor immediately to reschedule before you run out of drug.


Before dilution, store at room temperature between 36 and 86 degrees F (2-30 degrees C) away from light and moisture. For information on product stability after dilution in the correct fluids, consult your pharmacist. Discard any unused portion of the ampule or cartridge.

Medical Alert

Your condition can cause complications in a medical emergency. For enrollment information call MedicAlert at 1-800-854-1166 (USA), or 1-800-668-1507 (Canada).