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Trimethobenzamide HCl oral

Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.





This medication is used to treat nausea and vomiting.

How To Use

Swallow capsules with a full glass of water or juice and take as directed by your doctor.

Side Effects

Diarrhea, headache, dizziness, drowsiness, dry mouth, or muscle cramps may occur. If any of these effects persist or become bothersome, inform your doctor. Notify your doctor if you experience any of the following: unusual bleeding, depression, confusion, tremors, involuntary movements of the eyes/face/limbs, muscle spasms, rash, mouth sores, vision changes, yellowing of the eyes or skin. If you notice other effects not listed above, contact your doctor or pharmacist.


Tell your doctor your medical history, especially: high fever, stomach problems (gastroenteritis), swelling/disease of the brain (encephalitis/encephalopathy), mineral (electrolyte) imbalance, any allergies. Do not give children trimethobenzamide to treat vomiting when the cause of vomiting is unknown. Trimethobenzamide may worsen Reye's Syndrome, a rare but serious illness. Do not give trimethobenzamide (or aspirin or acetaminophen) to a child with symptoms of Reye's Syndrome (sudden, severe, persistent vomiting; drowsiness or stupor; unusual behavior; and seizures). Call the doctor immediately if these symptoms are present. Children and teenagers should not use this drug if they have chickenpox, influenza, or any undiagnosed illness without first consulting a doctor about Reye's syndrome. Limit alcohol intake because it adds to the drowsiness and dizziness effects of trimethobenzamide. If dizziness or drowsiness occurs, use caution engaging in activities requiring alertness such as driving. This medication should be used only if clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known if this medication is excreted into breast milk. Consult your doctor before breast-feeding.

Drug Interactions

Tell your doctor of all prescription and nonprescription medications you may use, especially: narcotic pain medication (e.g., codeine), sleeping pills, tranquilizers, sedatives, barbiturates (e.g., phenobarbital), drowsiness-causing antihistamines (e.g., diphenhydramine). Do not start or stop any medicine without doctor or pharmacist approval.


If overdose is suspected, contact your local poison control center or emergency room immediately.


If vomiting occurs just after taking a capsule, the medication may not have had a chance to be absorbed. In these cases, use of the suppositories are recommended. Discuss this with your doctor or pharmacist. Do not allow anyone else to take this medication.

Missed Dose

Take any missed dose as soon as possible but not if it is almost time for the next dose. If it is time for the next dose, skip the missed dose and resume your regular schedule. Do not double the dose to catch up.


Store at room temperature and keep away from moisture and sunlight. Do not store in the bathroom.