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Tretinoin and Mequinol topical

Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.





This medication is used to treat brown "age" or "liver" spots (solar lentigines).

How To Use

Read the Medication Guide provided by your pharmacist. If you have any questions regarding the information, ask your doctor or pharmacist. Apply this medication to the skin to be treated using the applicator tip usually twice daily at least 8 hours apart or as directed by your doctor. Important not to apply to surrounding skin as temporary lightening of the skin surrounding the treated skin (halo hypopigmentation) may occur. This medication is for use on the skin only. Avoid contact with the eyes. Do not use more than prescribed, apply this more often or use this for longer than prescribed. Your condition will not clear faster, but risk of side effects may be increased. Do not shower or bathe the treated skin for at least 6 hours after applying this medication. Cosmetics may be applied 30 minutes after applying this drug.

Side Effects

Temporary stinging, burning, irritation, peeling, redness, itching, or dry skin may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. An allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.


Before using this medication, tell your doctor or pharmacist your medical history, especially of: vitiligo, eczema, any allergies. This medication may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths or sunlamps. Wear protective clothing when outdoors. This medication must not be used during pregnancy. If you become pregnant or think you may be pregnant, inform your doctor immediately. It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding.

Drug Interactions

This drug should not be used with the following medications because there may be increased sensitivity to the sun: thiazides (e.g., hydrochlorothiazide), tetracycline antibiotics, quinolone antibiotics (e.g., ciprofloxacin), phenothiazines (e.g., chlorpromazine), sulfa drugs. Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription products you may use, especially of: other skin products. Do not start or stop any medicine without doctor or pharmacist approval.


If overdose is suspected, contact your local poison control center or emergency room immediately. This medicine may be harmful if swallowed.


Follow a comprehensive sun protection program, before and after using this medication. Ask your doctor or pharmacist for more details. Do not share this medication with others.

Missed Dose

If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.


Store at room temperature between 59 and 86 degrees F (15-30 degrees C) away from light, moisture, and open flame. Do not store in the bathroom. Keep all medicines away from children and pets.