Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.

THIOGUANINE - ORAL

(thigh-oh-GWAN-een)

Uses

Thioguanine is used to treat certain types of leukemia.

How To Use

This is a potent medication. Take it exactly as prescribed. Unless your doctor instructs you otherwise, drink plenty of fluids while taking this medication. This helps your kidneys to remove the drug from your body and avoid some of the side effects. Do not stop taking this medication, even if you feel nauseated or experience vomiting. If you vomit shortly after a dose, contact your doctor.

Side Effects

Nausea, vomiting, diarrhea, loss of appetite, skin rash and itchiness are common side effects. Taking the drug on an empty stomach with a full glass of water may help relieve vomiting. Changes in diet, such as eating several small meals or limiting activity may help lessen some of these effects. In some cases, drug therapy may be necessary to prevent or relieve nausea and vomiting. Contact your doctor without delay if you experience any of the following symptoms: fever, chills, painful or difficult urination, easy bruising or bleeding, black tarry stools, blood in urine or stools, lower back or side pain, cough, sores in mouth or on lips, yellowing eyes or skin, joint pain, swelling of feet or lower legs, unsteady walking. If you notice other effects not listed above, contact your doctor or pharmacist.

Precautions

Contraceptive (birth control) measures are recommended for use in men and women while taking this medication. This medication is not recommended for use during pregnancy. Consult your doctor. It is not known if this drug passes into breast milk. Consult your doctor before breast-feeding.

Drug Interactions

Tell your doctor of all prescription and nonprescription drugs you may use, especially of: medicine used to treat gout. Do not start or stop any medicine without doctor or pharmacist approval.

Overdose

If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include nausea, vomiting, sweating, and weakness.

Notes

This medication can lower your body's ability to fight an infection. Notify your doctor if you develop any signs of an infection such as fever, sore throat, rash, or chills. Avoid touching your eyes or inside your nose without first washing your hands. Use caution with sharp objects like safety razors or nail cutters and avoid activities such as contact sports in order to lower the chance of getting cut, bruised or injured. Do not have immunizations/vaccinations without consent of your doctor, and avoid contact with people who have recently received oral polio vaccine. Regular doctor visits are important. Frequent blood tests will be done to monitor therapy.

Missed Dose

Take it as soon as remembered but if almost time for your next dose, skip the missed dose and resume your regular schedule. Do not double dose to "catch up."

Storage

Store at room temperature away from heat and sunlight. Do not store in the bathroom.

Medical Alert

Your condition can cause complications in a medical emergency. For enrollment information call MedicAlert at 1-800-854-1166 (USA), or 1-800-668-1507 (Canada).