Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.

THIETHYLPERAZINE - RECTAL SUPPOSITORY

(thigh-ETH-ill-PAIR-uh-zeen)

Uses

This medication is used to treat nausea and vomiting.

How To Use

This medication is for rectal use only. If wrapped, remove the wrapping from the suppository before using. Gently insert one suppository into the rectum by pushing lightly with a finger. Wash hands after use. Do not use this more often or increase your dose without consulting your doctor. Your condition will not improve any faster but the risk of side effects will be increased.

Side Effects

Constipation, drowsiness, vision changes or dry mouth may occur. If any of these effects persist or worsen, notify your doctor. Unlikely to occur, but report promptly: restlessness, muscle stiffness, weakness, difficulty speaking, loss of balance, mask- like facial expression, trembling or shaking, dizziness, lip smacking or other uncontrollable movements, difficulty urinating, skin rash/discoloration. Very unlikely to occur, but report promptly: sore throat, unusual bleeding or bruising, stomach pain, yellowing of eyes or skin, dark urine, hot dry skin, vomiting. Though very unlikely to occur, notify your doctor immediately if you experience any of the following effects: severe muscle stiffness, confusion, fever, seizures, irregular/fast heartbeat, increased sweating, prolonged/painful erection. In the unlikely event you have an allergic reaction to this drug, seek immediate medical attention. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.

Precautions

Tell your doctor your medical history, especially of: liver disease, seizure disorders, blood disorders, glaucoma, parkinsonism, asthma, allergies (especially drug allergies). Because this medication may cause drowsiness, use caution operating machinery or engaging in activities requiring alertness. This medication may make you more sensitive to the sun. Avoid prolonged sun exposure. Wear protective clothing and use a sunscreen when outdoors. It is recommended to avoid alcohol while using this medication. The manufacturer of this medication states this drug should not be used during pregnancy. If you become pregnant or think you may pregnant, inform your doctor immediately. It is not known if this medication is excreted into breast milk. Consult your doctor before breast-feeding.

Drug Interactions

Tell your doctor of all prescription and nonprescription medications you use, especially of: anti-anxiety drugs, antidepressants, muscle relaxants, anti-seizure drugs, high blood pressure drugs, atropine-like drugs, narcotic pain relievers (e.g., codeine), sleeping pills, cisapride, lithium, sparfloxacin, grepafloxacin, guanethidine, guanadrel, metrizamide, cabergoline, drowsiness-causing antihistamines (e.g., diphenhydramine), other drugs that make you drowsy. Many cough-and-cold products contain ingredients that may add a drowsiness effect. Before using cough-and-cold medications, ask your doctor or pharmacist about the safe use of those products. Do not start or stop any medicine without doctor or pharmacist approval.

Overdose

If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include muscle spasms of face or neck, confusion, seizures, lightheadedness, and slowed breathing.

Notes

This medication is also available as a tablet and an injection. Do not share this medication with others.

Missed Dose

Use each dose at the scheduled time. However, if you miss a dose, use it as soon as remembered; do not use it if it is near the time for the next dose, instead, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.

Storage

Store this medication below 77 degrees F (25 degrees C) away from heat and light. Do not store in the bathroom. Keep this and all medications out of the reach of children.

Medical Alert

Your condition can cause complications in a medical emergency. For enrollment information call MedicAlert at 1-800-854-1166 (USA), or 1-800-668-1507 (Canada).