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Succimer oral

Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.





This medication is used for treatment of lead poisoning.

How To Use

Take this medication by mouth, generally for a 19 day course of treatment, as directed by your doctor. If further treatment is necessary, it will usually begin after a 2 week break. Do not take this medication for longer than 3 weeks without a break. The number of courses of treatment is based on your medical condition and response to therapy. Take this medication exactly as prescribed. Do not stop using this medication unless told to do so by your doctor. If the patient is unable to swallow capsules, the capsules may be opened and the contents sprinkled on soft food or placed on a spoon and taken with fruit juice. Drink plenty of fluids while you are on this medication.

Side Effects

Nausea, vomiting, loss of appetite, loose stools, metallic taste in mouth, drowsiness, dizziness, watery eyes and headache may occur. If these effects persist or worsen, notify your doctor promptly. Tell your doctor immediately if you have any of these serious side effects: blood in stool, back or stomach pain, tingling or numbness of hands or feet, rash, mouth sores. Tell your doctor immediately if you have any of these unlikely but serious side effects: irregular heartbeat, change in the amount of urine, persistent sore throat, persistent fever. If you notice other side effects not listed above, contact your doctor or pharmacist.


Tell your doctor your medical history, including: kidney or liver disease, previous treatment for lead poisoning, any allergies. This drug may make you dizzy or drowsy; use caution engaging in activities requiring alertness such as driving or using machinery. Limit alcoholic beverages. This medication can lower the body's ability to fight an infection. Notify your doctor promptly if you develop any signs of infection such as fever, chills, or persistent sore throat. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known whether this drug passes into breast milk. Because of the potential risk to the infant, breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding.

Drug Interactions

Tell your doctor of all prescription and nonprescription drugs you may use, especially of: other chelating agents (e.g., calcium EDTA). Also report any medications you take that can cause drowsiness, such as: sleeping pills, sedatives, tranquilizers, anti-anxiety drugs (e.g., diazepam), narcotic pain relievers (e.g., codeine), psychiatric medicines, anti-seizure drugs, muscle relaxants, certain antihistamines (e.g., diphenhydramine). Check the labels on all your medicines (e.g., cough-and- cold products) because they may contain drowsiness-causing ingredients. Ask your pharmacist about the safe use of those products. This medication may interfere with certain lab tests. Notify laboratory personnel that you are using this medication. This medication can cause false positive results for ketones in urine when using certain reagent strips (e.g., Ketostix). Do not start or stop any medicine without doctor or pharmacist approval.


If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose include loss of appetite, vomiting, and blood in vomit or stool.


Do not share this medication with others. It is important to remove the source of lead exposure. Consult your doctor or pharmacist for details on identifying and avoiding sources of lead exposure. Blood lead levels, laboratory and medical tests will be performed to monitor for side effects or response to treatment.

Missed Dose

If you miss a dose, consult your doctor or pharmacist to establish a new dosing schedule.


Store at room temperature between 59 and 77 degrees F (15 - 25 degrees C) away from light and moisture.

Medical Alert

Your condition can cause complications in a medical emergency. For enrollment information call MedicAlert at 1-800-854-1166 (USA), or 1-800-668-1507 (Canada).