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Pseudoephedrine HCl and Terfenadine oral

Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.


(sue-doh-eff-ED-rin WITH ter-FEN-uh-deen)



This medication contains a decongestant (pseudoephedrine) and an antihistamine (terfenadine). Decongestants are used to relieve nasal stuffiness. Antihistamines provide relief of symptoms of allergies and hay fever, such as watery and itching eyes, runny nose and sneezing. This drug (terfenadine) has been withdrawn from the U.S. market due to safety or effectiveness problems.

How To Use

Take this medication by mouth as directed, usually twice a day. This may be taken with food or after meals if stomach upset occurs. Do not increase your dose or take this more often than directed.

Side Effects

Insomnia, nervousness, headache, dry mouth and mild stomach upset may occur. These effects should subside as your body adjusts to the medication. Call your doctor should they persist. Unlikely to occur but notify your doctor immediately if you experience: irregular heartbeat, dizziness, abdominal pain, light-colored stools, yellowing of the eyes or skin. If you notice other effects not listed above, contact your doctor or pharmacist.


Tell your doctor if you have: heart problems, liver problems, kidney problems, thyroid disease, high blood pressure, glaucoma, prostate trouble, diabetes, allergies (especially drug allergies). This medication should be used only if clearly needed during pregnancy. Discuss the risks and benefits with your doctor. Since small amounts of this medication are found in breast milk, consult your doctor before breast-feeding.

Drug Interactions

Before using this drug, tell your doctor of all drugs you may use (both prescription and nonprescription) especially of: erythromycin or drugs related to it (e.g., clarithromycin, troleandomycin), azole antifungals (e.g., ketoconazole, itraconazole), mibefradil, protease inhibitors (e.g., ritonavir, saquinavir), SSRI antidepressants (e.g., fluvoxamine, sertraline), nefazodone, zileuton, high blood pressure drugs, asthma drugs, heart drugs. Also report the use of drugs that can affect the heart by prolonging the QC interval such as: astemizole, cisapride, grepafloxacin, sparfloxacin, phenothiazines such as chlorpromazine, tricyclic antidepressants such as amitriptyline. Do no take this drug for several days before allergy testing as test results may be affected. Do not eat grapefruit or drink grapefruit juice unless your doctor instructs you otherwise. Do not start or stop any medicine without doctor or pharmacist approval.


If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include unusual drowsiness or dizziness, nausea, vomiting, fast or irregular heartbeat, sweating, tremors, fever, and seizures.


Do not take this medication for several days before allergy testing since test results can be affected. Do not share this drug with others.

Missed Dose

If you miss a dose, take it as soon as remembered; do not take it if it is near the time for the next dose, instead, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.


Store at room temperature between 59 and 86 degrees F (15 and 30 degrees C) away from heat and light. Do not store in the bathroom.