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Potassium citrate oral

Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.


(poh-TASS-ee-um SYE-trate)



This medication makes the urine less acidic. It is used in the treatment of certain kidney disorders and gout. It may also be used with certain antibiotics to make them more effective.

How To Use

Take this medication as prescribed, usually three times a day. Take this with meals or within 30 minutes after a meal to reduce stomach upset. Swallow each tablet whole followed by a full glass (8 oz or 240 ml) of water. Do not suck, chew or crush the tablets. Do not lie down for 30 minutes after taking this medication. Do not increase your dose or take this more often without your doctor's approval.

Side Effects

Stomach upset, nausea, vomiting, or loose stools may occur the first few days as your body adjusts to the medication. If these effects continue or become bothersome, inform your doctor. Notify your doctor if you develop: severe vomiting, stomach pain, unusual weakness, mental changes, muscle pain, rapid or irregular heartbeat, breathing trouble, tingling or numbness of the hands or feet, black tarry stools, unpleasant taste, nervousness. If you notice other effects not listed above, contact your doctor or pharmacist.


Tell your doctor if you have: kidney problems, heart disease, Addison's disease, high blood pressure, drug allergies. This medication should be used only if clearly needed during pregnancy. Discuss the risks and benefits with your doctor. Since small amounts of this medication are found in breast milk, consult your doctor before breast-feeding.

Drug Interactions

Tell your doctor of any over-the-counter or prescription medication you may take, including: aspirin, water pills, potassium supplements, salt substitutes, steroids, medication for high blood pressure, quinidine, antacids, methenamine, ACE inhibitors (e.g., benazepril, captopril). Do not start or stop any medicine without doctor or pharmacist approval.


If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include sluggishness, weakness, confusion, irregular heartbeat, or fainting.


While taking this medication it may be necessary for you to test the pH (acidity) of your urine using special test paper. The pH helps determine the proper dose. Do not be alarmed if a 'whole' tablet appears in the stool. It is the empty shell of the tablet.

Missed Dose

If you miss a dose, take it as soon as remembered; do not take it if it is near the time for the next dose, instead, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.


Store at room temperature between 59 and 86 degrees F (15 and 30 degrees C) away from heat, light and moisture. Do not store in the bathroom.