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Nilutamide oral

Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.




WARNING: Nilutamide may infrequently cause lung problems (interstitial pneumonitis), which rarely may be fatal. Seek immediate medical attention if any of these unlikely but serious side effects occur: trouble breathing, persistent cough, chest pain, fever. Laboratory and/or medical tests (e.g., chest X-ray, lung function) may be performed to monitor your progress.


This medication is used, in addition to surgery, to treat prostate cancer.

How To Use

Take by mouth, generally once daily, as directed. This medication can be taken with or without food. Do not stop taking this without consulting your doctor or pharmacist.

Side Effects

Nausea, constipation, loss of appetite or hot flashes may occur. If these effects persist or worsen, notify your doctor. Report promptly: stomach pain, headache, vision changes, facial flushing, dizziness, mental/mood changes, trouble sleeping, sweating, loss of body hair, rash, changes in sense of touch, decreased sex drive. Unlikely but report promptly: trouble breathing, cough, chest pain, fever, yellowing of the eyes or skin, dark urine, unusual tiredness, swelling, diarrhea, itching, black or bloody stools. If you notice other effects not listed above, contact your doctor or pharmacist.


Tell your doctor your medical history, including: any allergies, liver disease, lung problems (e.g., asthma, COPD). This medication can cause a reaction when used with alcohol, including facial flushing, tiredness or dizziness. If you experience these effects, avoid alcohol while taking this. Consult your doctor or pharmacist about the use of alcohol. This medication may alter the ability of your eye to adjust from a lighted area to a dark area. Use caution when driving at night or through tunnels. The use of tinted glasses may help block this effect. Consult your doctor or pharmacist. Use with caution in patients of Asian descent, as they may be more sensitive to the effects of this drug. Consult your doctor. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known whether this drug is excreted into breast milk. Consult your doctor before breast-feeding.

Drug Interactions

Tell your doctor of all prescription and nonprescription medication you use, especially of: theophylline, drugs that affect your liver (e.g., isoniazid), "blood thinners" (anticoagulants such as warfarin), seizure medications (e.g., phenytoin, carbamazepine). Do not start or stop any medicine without doctor or pharmacist approval.


If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include nausea, vomiting, dizziness, and general discomfort.


Do not share this medication with others. Laboratory and/or medical tests, including chest x-rays or liver function tests, may be performed to monitor for side effects and response to therapy.

Missed Dose

If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.


Store at room temperature between 59 and 86 degrees F (15 to 30 degrees C) away from light and moisture.