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Nevirapine oral
NEVIRAPINE SUSPENSION - ORAL

Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.

NEVIRAPINE SUSPENSION - ORAL

(neh-VYE-ruh-peen)

COMMON BRAND NAME(S): Viramune

WARNING: Because HIV can quickly become resistant to this medication if used alone, nevirapine must be used with at least 1 other anti-HIV medication. Your doctor may change your treatment plan if this medication stops working well. Nevirapine has caused severe, even fatal, liver and skin reactions (e.g., Stevens-Johnson syndrome, allergic reaction). If you develop a rash while using this medication, stop using nevirapine and notify your doctor immediately. If you develop unusual fatigue, abdominal or stomach pain, dark urine, nausea, loss of appetite, or yellowing of the skin or eyes, seek immediate medical attention.

Uses

This medication is used in the treatment of HIV virus (the virus that causes AIDS). It is used in combination with other HIV-fighting medications.

How To Use

Shake gently before each dose and take exactly as directed by your doctor. Dosage for the first 14 days is lower to minimize rash occurrence. Nevirapine is taken with at least one other antiretroviral medication for HIV. If a rash develops in the first two weeks, do not increase the dose until the rash is gone. Consult your doctor. If treatment is stopped for more than 7 days, re-starting this drug should follow the same dosing pattern as before.

Side Effects

Nausea or headache may occur. Notify your prescriber if these problems persist or worsen. Notify your prescriber immediately if you develop: a rash, itching, fever, blistering, mouth sores, pink eye (conjunctivitis), swelling, muscle/joint aches, yellowing of the skin or eyes, stomach pain, tingling or numb hands or feet. Changes in body fat may occur while you are taking this medication (e.g., increased fat in the upper back and stomach areas, decreased fat in the arms and legs). The cause and long-term effects of these changes are unknown. Discuss the risks and benefits of therapy with your doctor, as well as the possible role of exercise to reduce this side effect. If you notice other effects not listed above, contact your doctor or pharmacist.

Precautions

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: severe liver disease. Tell your doctor your medical history, especially of: liver disease, severe kidney disease, allergies (especially drug allergies). This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. Nevirapine is excreted into breast milk. Because breast milk can transmit HIV, do not breast-feed.

Drug Interactions

This drug is not recommended for use with: ketoconazole. Ask your doctor or pharmacist for more details. Inform your prescriber or pharmacist about all the medicines you may use (both prescription and non-prescription), especially of: protease inhibitors (e.g., indinavir, lopinavir, saquinavir), efavirenz, terfenadine, astemizole, alprazolam, triazolam, nifedipine, cyclosporine, corticosteroids (e.g., prednisone, hydrocortisone), macrolide antibiotics (e.g., erythromycin, clarithromycin), rifamycins (e.g., rifampin, rifabutin), methadone, cimetidine, St John's wort. This drug may interfere with the effectiveness of birth control pills. Discuss using other methods of birth control with your doctor. Do not start or stop any medicine without doctor or pharmacist approval.

Overdose

If overdose is suspected, contact your local poison control center or emergency room immediately.

Notes

The long-term effects of nevirapine are unknown at this time. Nevirapine has not been shown to reduce the chance of transmitting the HIV virus to others. No cure exists for HIV infection and the illnesses associated with your disease (infections, etc.) may continue. Laboratory tests (e.g., liver function) will be performed in order to monitor for drug side effects.

Missed Dose

If you miss a dose, use it as soon as you remember. If it is within 2 hours of the next dose, skip the missed dose and resume your usual dosing schedule. It is important not to miss doses of this drug.

Storage

Store at room temperature between 59 and 86 degrees F (15 to 30 degrees C) away from moisture and light as directed. Do not store in the bathroom. Keep in a tightly closed bottle.