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Lymphocyte immune globulin intraven.
LYMPHOCYTE IMMUNE GLOBULIN, ANTI-THYMOCYTE GLOBULIN (HORSE)-INJ

Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.

LYMPHOCYTE IMMUNE GLOBULIN, ANTI-THYMOCYTE GLOBULIN (HORSE)-INJ

(LIM-foe-site, AN-ti THIGH-mow-site)

COMMON BRAND NAME(S): Atgam

Uses

This medication is used to prevent rejection after organ transplant (e.g., kidney) or to treat certain blood disorders (e.g., aplastic anemia).

How To Use

Give this medication by vein (IV), usually over at least four hours or as directed by your doctor. A skin test is recommended before the first dose to test for sensitivity to this medication. Consult your doctor or pharmacist for details. You might receive other medications (e.g., antihistamines, corticosteroids, and/or antipyretics), in order to the minimize side effects of this drug. Consult your doctor or pharmacist for details, including how and when to take additional medications. Follow all instructions for proper dilution with correct IV fluids. Do not shake this medication. Follow all safety precautions for this medication. Consult your pharmacist for details. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid.

Side Effects

Nausea or chills may occur. If any of these effects persist or worsen, contact your doctor or pharmacist. Tell your doctor immediately if any of these serious side effects occur: fever, persistent sore throat, easy bleeding or bruising. Tell your doctor immediately if any of these unlikely but serious side effects occur: dizziness, joint or muscle pain, back or chest pain, diarrhea, headache, pain or redness at the injection site, sores in the mouth or throat, sores on genitals, unusual sweating, pain or redness in the legs or arms, stomach pain, bloating, mental/mood changes, black or bloody stools, tremors, unusual fatigue. Tell your doctor immediately if any of these highly unlikely but very serious side effects occur: seizures, tingling of the hands or feet, fast/slow/irregular pulse, yellowing eyes, dark urine, change in the amount of urine. An allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include: rash, itching, swelling, severe dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.

Precautions

Tell your doctor your medical history, especially of: blood cell problems (e.g., leukopenia, thrombocytopenia), previous use of lymphocyte immune globulin, any allergies. This drug may make you dizzy. Use caution when engaging in activities requiring alertness such as driving or using machinery. Limit alcoholic beverages because they can intensify the dizziness effect of this medication. This medication can lower the body's ability to fight an infection. Notify your doctor promptly if you develop any signs of an infection such as fever, chills, or persistent sore throat. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known if this drug passes into breast milk. Consult your doctor before breast-feeding.

Drug Interactions

Tell your doctor or pharmacist of all prescription and nonprescription drugs you may use, especially of: corticosteroid drugs (e.g., prednisone, methylprednisolone), other drugs that suppress the immune system (e.g., azathioprine). Do not start or stop any medicine without doctor or pharmacist approval.

Overdose

If overdose is suspected, contact your local poison control center or emergency room immediately.

Notes

Do not share this medication with others. Laboratory and/or medical tests may be performed to monitor for side effects and response to treatment.

Missed Dose

It is important to receive this drug exactly as prescribed. However, if you miss a dose, contact your doctor or pharmacist immediately to establish a new dosing schedule. If the dose is interrupted, contact your doctor or pharmacist immediately to establish new dosing.

Storage

Store ampoules in a refrigerator between 36 and 46 degrees F (2 and 8 degrees C) away from light and moisture. Do not freeze. Consult your pharmacist for details regarding the stability of the drug after dilution in correct IV fluids. Discard any unused liquid.

Medical Alert

Your condition can cause complications in a medical emergency. For enrollment information call MedicAlert at 1-800-854-1166 (USA), or 1-800-668-1507 (Canada).