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Lymphocyte immu glob.,rabbit intraven.
LYMPHOCYTE IMMUNE GLOBULIN, ANTI-THYMOCYTE GLOBULIN (RABBIT)-INJ

Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.

LYMPHOCYTE IMMUNE GLOBULIN, ANTI-THYMOCYTE GLOBULIN (RABBIT)-INJ

(LIM-foe-site, AN-ti THIGH-mow-site)

COMMON BRAND NAME(S): Thymoglobulin

WARNING: This medication should only be used by health care professionals trained in the use of immunosuppressive therapy. Due to the potential for serious side effects (e.g., allergic reaction, decreased immune system function), your response to therapy will need to be followed closely by your doctor. See Side Effects and Precautions for more information.

Uses

This medication is used to treat rejection after organ transplant (e.g., kidney transplant).

OTHER

Uses

This medication may also be used for the treatment of certain blood disorders (aplastic anemia).

How To Use

Give this medication by vein (IV), as directed by your doctor. You might receive other medications (e.g., acetaminophen, corticosteroids, and/or an antihistamine) in order to decrease the side effects of this drug. Consult your doctor or pharmacist for details, including how and when to take additional medications. You might receive other medications to help prevent rejection of the transplant organ (e.g., corticosteroids, azathioprine) and/or prevent infection (e.g., antibiotics, antifungals, antivirals). Take these medications exactly as prescribed by your doctor. Consult your doctor or pharmacist if you are unsure how to take any of your medications. Follow all directions for proper mixing and dilution with correct IV fluids. Follow all safety precautions for this medication. Consult your pharmacist for details. Before using, check this medication visually for particles or discoloration. If either is present, do not use the liquid.

Side Effects

Nausea, chills or headache may occur. If any of these effects persist or worsen, notify your doctor promptly. Tell your doctor immediately if any of these serious side effects occur: fever, dizziness, diarrhea, stomach pain, unusual fatigue, joint or muscle pain, persistent sore throat, easy bleeding or bruising, fast or irregular pulse. An allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include: rash, itching, swelling, severe dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.

Precautions

This medication is not recommended for use if you have the following medical conditions: current viral illness, allergy to rabbit proteins. Tell your doctor your medical history, especially of: blood cell problems (e.g., leukopenia, thrombocytopenia), previous use of anti-thymocyte globulin, any allergies you may have. This medication may make you dizzy. Use caution when engaging in activities requiring alertness such as driving or using machinery. Limit alcoholic beverages because they can increase the dizziness effect of this medication. Notify your doctor promptly if you develop any signs of an infection, such as fever, chills or persistent sore throat. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding.

Drug Interactions

Tell your doctor of all prescription and nonprescription medication you may use, especially: corticosteroid drugs (e.g., methylprednisolone, prednisone), other drugs that suppress the immune system (e.g., azathioprine, cyclosporine), rabbit-derived products (immune globulins). Do not start or stop any medicine without doctor or pharmacist approval. This medication can affect the results of certain lab tests. Make sure laboratory personnel and your doctors know you use this drug.

Overdose

If overdose is suspected, contact your local poison control center or emergency room immediately.

Notes

Laboratory and/or medical tests (e.g., blood tests ) should be performed to monitor your progress. Keep all doctor appointments and lab visits so your therapy can be monitored closely.

Missed Dose

It is important to receive this drug exactly as prescribed. However, if you miss a dose, contact your doctor or pharmacist immediately to establish a new dosing schedule. If the dose is interrupted, contact your doctor or pharmacist immediately to establish new dosing.

Storage

Store vials in a refrigerator between 36 and 46 degrees F (2 to 8 degrees C) away from light and moisture. Do not freeze. Consult your pharmacist for details regarding the stability of the drug after dilution in IV fluids. Discard any unused liquid.

Medical Alert

Your condition can cause complications in a medical emergency. For enrollment information call MedicAlert at 1-800-854-1166 (USA), or 1-800-668-1507 (Canada).