Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.

ACETAMINOPHEN/ISOMETHEPTENE/DICHLORALPHENAZONE - ORAL

(uh-seet-uh-MEE-no-fen/eye-so-meth-EP-teen/dye-klor-al-FEN-uh- zone)

COMMON BRAND NAME(S): Amidrine, Atarin, Isocom, Midchlor, Midrin

Uses

This medication is used to relieve migraine and tension headaches.

How To Use

Take this medication exactly as prescribed. Do not increase your dose or take this more often than directed. For migraine headaches, take two capsules at the first sign of an attack. Then take one capsule every hour as needed until the headache is relieved. Do not take more than 5 capsules in a 12 hour period. In tension headaches, usually no more than 8 capsules a day are recommended. Do not exceed the maximum dose prescribed. This medication contains acetaminophen. Do not take more acetaminophen than recommended (see Side Effects section).

Side Effects

Dizziness may occur as your body adjusts to the medication. If this effect continues or becomes bothersome, inform your doctor. If you do not have liver problems, the adult maximum dose of acetaminophen is 4 grams per day (4000 milligrams). If you take more than the maximum daily amount, it may cause serious (possibly fatal) liver disease. Tell your doctor immediately if you have any of the following symptoms of liver damage: severe nausea, yellowing eyes or skin, dark urine, stomach pain, extreme fatigue. An allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include: rash, itching, swelling, severe dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.

Precautions

Tell your doctor if you have: heart disease, glaucoma, kidney disease, liver disease, high blood pressure, allergies (especially drug allergies). This product contains acetaminophen. Acetaminophen may cause liver damage. Daily use of alcohol, especially when combined with acetaminophen, may increase your risk for liver damage. Check with your doctor or pharmacist for more information. This medication should be used only if clearly needed during pregnancy. Discuss the risks and benefits with your doctor. Since small amounts of this medication are found in breast milk, consult your doctor before breast-feeding.

Drug Interactions

Tell your doctor of any over-the-counter or prescription medication you may take or have recently taken, including: antidepressants, MAO inhibitors (e.g., furazolidone, linezolid, phenelzine, selegiline, tranylcypromine). Acetaminophen is an ingredient in many nonprescription products and in some combination prescription medications. Read the labels carefully before taking other pain relievers, fever reducers, or cold products to see if they also contain acetaminophen. Consult your pharmacist if you are uncertain if your other prescription or nonprescription products contain acetaminophen. (Also see maximum daily dose information in Side Effects section). Do not start or stop any medicine without doctor or pharmacist approval.

Overdose

If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include: severe nausea, vomiting, yellowing eyes or skin, stomach pain, dark urine, extreme fatigue, headache, agitation, low body temperature, rapid and shallow breathing, unusually rapid or slow heartbeat, and unresponsiveness.

Notes

Use caution while driving or doing tasks requiring alertness as this medication may cause drowsiness or dizziness. Notify your doctor if this medication fails to relieve your headaches.

Missed Dose

If you miss a dose, take it as soon as remembered; do not take it if it is near the time for the next dose, instead, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.

Storage

Store at room temperature between 59 and 86 degrees F (15 to 30 degrees C) away from heat and light. Do not store in the bathroom.