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Hydroxocobalamin intramusc.

Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.




Hydroxocobalamin is a man-made (synthetic) form of vitamin B12; a vitamin that helps the body with blood and nerve function, cell production, and growth. Some medical conditions (e.g., various GI problems, cancer, infections) may cause low levels of vitamin B12 in the body.



This vitamin may also be used to treat a variety of other medical conditions including: multiple sclerosis, nerve problems (e.g., neuropathies), viral hepatitis, certain thyroid conditions (e.g., thyrotoxicosis), sterility, and malnutrition.

How To Use

Inject this medication into a muscle (IM) as directed by your doctor. Initially, it is usually given once daily but may later be changed by your doctor to once monthly (for maintenance). This medication should not be mixed with certain other injectable medications. Doing so could make this drug ineffective. Consult your pharmacist for details. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Learn how to store and discard needles and medical supplies safely. Consult your pharmacist.

Side Effects

Mild diarrhea, itching, or a feeling of general swelling may occur. If any of these effects persist or worsen, notify your doctor. Tell your doctor immediately if any of these unlikely but serious side effects occur: pain in the groin or lower legs, trouble breathing, swelling of the hands and feet, unusual weakness/fatigue, chest pain. An allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include: rash, severe swelling, dizziness. If you notice other effects not listed above, contact your doctor or pharmacist.


Tell your doctor your medical history, especially of: low potassium levels, gout, certain eye diseases (e.g., Leber's disease), other vitamin deficiencies, any allergies. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. Based on information of related products, this medication may pass into breast milk. Therefore, consult your doctor before breast-feeding.

Drug Interactions

Tell your doctor of all prescription and nonprescription medication you may use, especially: chloramphenicol. This product can affect the results of certain lab tests. Make sure laboratory personnel and your doctors know you use this product. Do not start or stop any medicine without doctor or pharmacist approval.


If overdose is suspected, contact your local poison control center or emergency room immediately.


Do not share this medication with others. Laboratory and/or medical tests (e.g., serum potassium) may be performed to monitor your progress. It is important to maintain a well-balanced diet to ensure adequate intake of all vitamins and minerals.

Missed Dose

If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.


Store at room temperature between 59 and 86 degrees F (15 and 30 degrees C) away from light.