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Hydralazine HCl and Reserpine oral

Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.


(hi-DRAL-uh-zeen WITH ree-SIR-peen)


Hydralazine and reserpine help to widen arteries and veins so blood flows better. This combination medication is used to treat high blood pressure (hypertension).

How To Use

Take this medication by mouth with food or milk as directed. Try to take it at the same time each day so you get into the habit of taking it. Do not stop taking this medication without first consulting your doctor. It is important to continue taking this medication even if you feel well. Most people with high blood pressure do not feel sick.

Side Effects

Dizziness, drowsiness, headache, lightheadedness, diarrhea, constipation, loss of appetite, nausea, loss of taste, flushing, fatigue or weakness may occur the first several days as your body adjusts to the medication. Weight gain, dry mouth, nasal congestion, mood changes, nervousness, dreams, nightmares, decreased sexual desire or ability and trouble urinating may also occur. If any of these effects continue or become bothersome, inform your doctor. To avoid dizziness and lightheadedness when rising from a seated or lying position, get up slowly. Also limit your intake of alcoholic beverages and avoid overheating which will aggravate these effects. Though unlikely to occur, notify your doctor if you develop: chest pain, rapid pulse, difficulty breathing, skin rash, fever, muscle aches, tingling of the hands or feet, mood changes, depression, difficulty sleeping, severe stomach upset, vomiting, jaundice, joint pain, change in the amount of urine. If you notice other effects not listed above, contact your doctor or pharmacist.


Tell your doctor if you have: kidney problems, heart disease, blood disorders, ulcers, depression, breast cancer, allergies (especially drug allergies). This medication should be used only if clearly needed during pregnancy. Discuss the risks and benefits with your doctor. Since small amounts of this medication are found in breast milk, consult your doctor before breast-feeding.

Drug Interactions

Tell your doctor of any over-the-counter or prescription medication you may take, especially of: all heart drugs, blood pressure medications, antidepressants. Do not take any medication for cough, colds, hay fever, allergies or weight control without first checking with your doctor or pharmacist. These medications may contain ingredients which can increase blood pressure. Do not start or stop any medicine without doctor or pharmacist approval.


If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include unusual dizziness; weakness; fast, irregular heartbeat; headache; flushing; sleepiness; slowed breathing; stiffness; leg pain; shaking; pinpoint pupils; and loss of consciousness.


It is important to have your blood pressure checked regularly while taking this medication. Learn how to take your blood pressure and understand the readings. Discuss this with your doctor or pharmacist.

Missed Dose

If you miss a dose, take it as soon as remembered; do not take it if it is near the time for the next dose, instead, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.


Store at room temperature between 59 and 86 degrees F (15 to 30 degrees C) away from heat and light. Do not store in the bathroom.