Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.

ZILEUTON - ORAL

(zigh-LEW-ten)

COMMON BRAND NAME(S): Zyflo

Uses

This medication is used for the prevention and treatment of chronic asthma. It is not intended for acute attacks.

OTHER

Uses

This drug may also be used to minimize breathing problems caused by exercising or sensitivity to aspirin.

How To Use

Take as directed. Do not exceed the prescribed dosage. Treatment can be continued, even during acute asthma attacks. Do not stop taking this medication unless directed to do so by your doctor. Do not decrease the dose or stop taking any other anti-asthma medication unless directed by your physician.

Side Effects

Nausea, drowsiness, constipation and dizziness may occur. If these continue or are bothersome, notify your doctor. Notify your doctor if you develop: stomach pain, unusual weakness. Unlikely, but report: yellowing of the skin or eyes, unusual fatigue or muscle aches, chest pain, insomnia. Notify your doctor immediately in the unlikely event an allergic reaction occurs. Symptoms include: difficulty breathing, skin rash, itching, fever. If you notice other effects not listed above, contact your doctor or pharmacist.

Precautions

Tell your doctor if you have: liver problems, allergies (especially drug allergies). Caution is advised when using this drug in elderly women because they may be more sensitive to the effects of the drug, especially liver toxicity. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known whether this drug is excreted into human milk. The manufacturer recommends you avoid breast-feeding while taking this drug. Consult your doctor. Asthmatic patients should always seek prompt medical attention if short-acting inhalers (bronchodilators) are needed more often than usual to treat wheezing or difficulty breathing. Limit alcohol intake due to the potential liver problems it can cause.

Drug Interactions

Tell your doctor of all nonprescription and prescription medication you may take, especially of: theophylline, warfarin, propranolol, terfenadine, astemizole. Do not start or stop any medicine without doctor or pharmacist approval.

Overdose

If overdose is suspected, contact your local poison control center or emergency room immediately.

Notes

Do not share this medication with anyone.

Missed Dose

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.

Storage

Store at room temperature between 68 and 77 degrees F (20-25 degrees C) away from light and moisture.

Medical Alert

Your condition can cause complications in a medical emergency. For enrollment information call MedicAlert at 1-800-854-1166 (USA), or 1-800-668-1507 (Canada).