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Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.





This medication is used to treat genital herpes, herpes infections of the skin, and oral herpes (i.e., cold sores). This medication does not cure herpes, but relieves the pain and may make the infection clear faster.

How To Use

Begin using this medication as soon as symptoms appear. Apply to all lesions as prescribed, usually every 3 hours 6 times a day for 7 days. Do not use more frequently than directed. Use a finger cot or rubber gloves to apply this to prevent spreading of the infection. Avoid applying this medication around the eyes.

Side Effects

This medication may cause burning, stinging or redness when first applied to the skin. This should disappear in a few days as your body adjusts to the medication. If these effects persist or worsen or a rash and itch occur, inform your doctor promptly. If you notice other effects not listed above, contact your doctor or pharmacist.


Tell your doctor your medical history, including: any allergies. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known if topical acyclovir is excreted into breast milk. Though to date there have been no reports of harm to nursing infants, consult your doctor before breast-feeding.

Drug Interactions

Inform your doctor about all the medicines you may use (both prescription and nonprescription), especially of: other antibiotic or corticosteroid (e.g., betamethasone) skin creams/ointments. Do not start or stop any medicine without doctor or pharmacist approval.


If overdose is suspected, contact your local poison control center or emergency room immediately. This medicine may be harmful if swallowed.


Avoid sexual activity while signs and symptoms of genital herpes are present to prevent infecting your partner. Do not share this medication with others.

Missed Dose

If you miss a dose, apply as soon as remembered and resume your usual dosing schedule. Do not "double-up" the dose to catch up.


Store at room temperature away from moisture and sunlight. Avoid freezing. Do not store in the bathroom. Keep all medicines away from children and pets.