Find & Manage Your Patient Assistance Programs
Estimated patient savings $600,000,000.00

Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.





This medication is used to prevent nausea and vomiting caused by cancer chemotherapy or after surgery. It works by blocking the hormone (serotonin) that causes vomiting.

How To Use

The first dose is injected 30 minutes before chemotherapy is begun. After chemo is completed, use as directed by your doctor, usually for 1 or 2 days after chemo is done.

Side Effects

Diarrhea or constipation, headache, lightheadedness or drowsiness (uncommon), as well as blurred vision may occur. If these effects persist or worsen, notify your doctor promptly. You may experience redness, irritation or swelling at the injection site. If this continues or becomes severe, contact your doctor. Very unlikely but report promptly: chest pain. In the unlikely event you have an allergic reaction to this drug, seek immediate medical attention. Symptoms of an allergic reaction include: rash, itching, swelling, severe dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.


Tell your doctor your medical history, especially of: stomach/intestinal problems (e.g., distension), liver disease, any allergies. Limit alcohol intake, as it may intensify drug side effects. Caution performing tasks requiring alertness (e.g., driving) until you know how this medication affects you. Tell your doctor if you are pregnant before using this medication. It is not known if this drug is excreted into breast milk. Consult your doctor before breast-feeding.

Drug Interactions

Tell your doctor of all the prescription and nonprescription drugs you may use. Do not start or stop any medicine without doctor or pharmacist approval.


If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include change in vision, severe constipation, severe dizziness, or irregular heartbeat.


Do not share this product with others.

Missed Dose

Try to take each dose at the scheduled time. If you miss a dose, take it as soon as remembered; do not take it if it is near the time for the next dose, instead, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.


The vials may be stored in or out of the refrigerator between 36 and 86 degrees F (2 and 30 degrees C) but should be protected from light. After adding it to a suitable IV fluid, this medication may be stored at room temperature for 48 hours (under normal light).