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Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.





This medication blocks acid in the stomach. It is used to treat and prevent ulcers, to treat gastroesophageal reflux disorder (GERD) and to treat conditions due to high acid secretion.

How To Use

This medication is given as an injection into a muscle (IM) or infused into a vein (IV) if one is unable to take oral medication. Premixed bags are for IV use only. Use this as prescribed. Do not increase your dose, use this more often than directed or stop using this without first consulting your doctor.

Side Effects

Headache, stomach upset or irritation or itching at the injection site may occur. If any of these effects continue or become bothersome, inform your doctor. Notify your doctor if you develop: a skin rash, rapid heart rate, swelling of the face, breathing trouble, unusual weakness, vision changes. Notify your doctor immediately if you notice: black tarry stools, coffee ground-like vomit (may indicate bleeding). If you notice other effects not listed above, contact your doctor or pharmacist.


Tell your doctor if you have: liver problems, kidney disease, heart rhythm disorders, allergies (especially drug allergies). This medication should be used only if clearly needed during pregnancy. Discuss the risks and benefits with your doctor. Since small amounts of this medication are found in breast milk, consult your doctor before breast-feeding.

Drug Interactions

Tell your doctor of all over-the-counter and prescription medication you may use, especially of: antacids, anti-anxiety medication, procainamide, theophylline, blood thinners, oral medication for diabetes, ketoconazole, itraconazole, triazolam. This medication is available in both prescription and over-the-counter formulations. Do not use both at the same time. Do not start or stop any medicine without doctor or pharmacist approval.


If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include difficulty breathing, fast heartbeat, tremors, vomiting, restlessness, weakness, fatigue, or dizziness.


For best results, this medication is used along with lifestyle changes such as stress reduction, exercise and dietary changes. Talk to your health care professional about changes you may benefit from. Laboratory tests will be done periodically to monitor the medication effects and to prevent side effects.

Missed Dose

If you miss a dose, use it as soon as remembered; do not use it if it is near the time for the next dose, instead, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.


The U.S. manufacturer recommends storing their vial between 39-77 degrees F (4-25 degrees C) away from heat and light. Brief storage up to 86 degrees F (30 degrees C) is permitted. Premixed IV bags may be refrigerated or stored between 36-77 degrees F (2-25 degrees C). The Canadian manufacturer recommends storing their vial between 36-77 degrees F (2-25 degrees C) away from heat and light.