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Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.




WARNING: This is a powerful fluid-reducing drug. Using too much of this drug can lead to serious water and mineral loss. Therefore, it is important you be monitored by your doctor. Promptly notify your doctor if you become very thirsty, have a dry mouth, become confused, or develop muscle cramps/weakness.


Bumetanide is a diuretic that decreases the amount of water retained in the body by increasing urination. Bumetanide is used to treat edema (fluid retention and swelling especially of the hands, feet and lungs caused by heart failure or kidney, liver and other diseases).



This drug may also be used for high blood pressure or to aid in clearing toxic drugs from the body.

How To Use

This medication is given by injection into a muscle (IM) or by vein (IV) in persons unable to use oral medication. Use this drug exactly as directed, along with all other prescribed medications and diets. Do not increase your dose, use this more often than prescribed or stop using this drug without consulting your doctor. The dosage is adjusted according to your response and condition being treated. The product should be checked for particles or discoloration before use.

Side Effects

Headache and nausea infrequently might occur. If these persist or worsen, notify your doctor. Unlikely but report promptly: muscle cramps or weakness, dizziness, difficulty breathing, one-sided weakness (arms and legs), unusual fatigue, unusual thirst. Very unlikely but report promptly: fainting episode, chest pain, hearing problems, unusual bleeding or bruising, yellowing of the eyes or skin. To prevent low potassium and other mineral deficiencies, this drug is frequently given with mineral supplements, food recommendations or certain water pills (potassium-sparing). In the unlikely event you have an allergic reaction to this drug, seek medical attention immediately. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.


Before using this drug, tell your doctor your medical history, including: any allergies (especially drug allergies), liver or kidney disease, blood disorders, hearing problems. Dizziness on standing may occur. To avoid dizziness or lightheadedness when rising from a seated or lying position, get up slowly. Also, limit your intake of alcoholic beverages which will aggravate these effects. A preservative (benzyl alcohol) which may be found in this product or in the liquid used to mix this product (diluent) can infrequently cause serious problems (sometimes death) if given by injection to an infant during the first months of life (neonatal period). The risk is greater with lower birth weight infants and is greater with increased amounts of benzyl alcohol. Symptoms include sudden gasping, low blood pressure, or a very slow heartbeat. Report these symptoms to the doctor immediately should they occur. If possible, a preservative-free product should be used when treating neonates. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known whether this drug is excreted into breast milk. Consult your doctor before breast-feeding. Caution is advised when this drug is used in the elderly.

Drug Interactions

Tell your doctor of all nonprescription and prescription medication you may use, especially of: other diuretics, (e.g., furosemide), digoxin, corticosteroids (e.g., prednisone), corticotropin, amphotericin B, lithium, ginseng, blood pressure medications, indomethacin (and other NSAIDs such as aspirin and ibuprofen), probenecid, drugs that cause ear or kidney problems (e.g., aminoglycosides such as gentamicin, or cisplatin). Do not start or stop any medicine without doctor or pharmacist approval.


If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include dry mouth, dizziness, excessive urination followed by a decrease in amount of urine, muscle cramps, weakness, and weak or irregular heartbeat.


Do not share this medication with others. Laboratory tests will be performed to monitor the use of this drug.

Missed Dose

If you miss a dose, consult your doctor or pharmacist to establish a new dosing schedule promptly.


Store at room temperature between 59 and 86 degrees F (15-30 degrees C) away from light and moisture.