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Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.




WARNING: This drug is a strong "water pill" (diuretic). Using too much of this drug can lead to serious water and mineral loss. Therefore, it is important you be monitored by your doctor. Promptly notify your doctor if you become very thirsty, have a dry mouth, become confused, or develop muscle cramps/weakness.


Bumetanide is a "water pill" (diuretic). It decreases the amount of water retained in the body by increasing urination. It is used to treat fluid retention in the lungs or swelling of the hands or feet (edema) or high blood pressure (hypertension).

How To Use

Take with food or milk to reduce stomach upset. If this medication is used in the late afternoon or evening, you may need to urinate during the night. Consult your doctor regarding your dosing schedule.

Side Effects

Headache and nausea infrequently might occur. If these persist or worsen, notify your doctor. Unlikely but report promptly: muscle cramps or weakness, dizziness, one-sided weakness (arms and legs), unusual fatigue, unusual thirst. Very unlikely but report promptly: fainting episodes, chest pain, hearing problems, unusual bleeding or bruising, yellowing of the eyes or skin. To prevent low potassium and other mineral deficiencies, this drug is frequently given with certain water pills (potassium-sparing) or mineral supplements/food recommendations. In the unlikely event you have an allergic reaction to this drug, seek medical attention immediately. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.


Tell your doctor your medical history, especially of: kidney problems, unusual decrease in urine output, liver disease, drug allergies. This drug can reduce the potassium levels in your blood. A potassium supplement may be prescribed by your doctor. This drug should be used during pregnancy only when clearly needed. Discuss the risks and benefits with your doctor. It is not known if this drug is excreted into breast milk. Consult your doctor before breast-feeding.

Drug Interactions

Tell your doctor of all nonprescription and prescription medication you use, especially of: other diuretics, (e.g., furosemide), digoxin, corticosteroids (e.g., prednisone), corticotropin, amphotericin B, lithium, ginseng, blood pressure medications, indomethacin (and other NSAIDs such as aspirin and ibuprofen), probenecid, drugs causing ear or kidney problems (e.g., aminoglycosides such as gentamicin; or cisplatin). Do not start or stop any medicine without doctor or pharmacist approval.


If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include dry mouth, dizziness, excessive urination followed by a decrease in amount of urine, muscle cramps, weakness, and weak or irregular heartbeat.


Do not share this medication with others.

Missed Dose

If you miss a dose, take as soon as remembered; do not take if it is almost time for the next dose, instead, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.


Store at room temperature between 59 - 86 degrees F (15 - 30 degrees C) away from moisture and light. Do not store in the bathroom.

Medical Alert

Your condition can cause complications in a medical emergency. For enrollment information call MedicAlert at 1-800-854-1166 (USA), or 1-800-668-1507 (Canada).