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Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.



COMMON BRAND NAME(S): Bellamine-S, Bellaspas, Bellergal-S


This medication is used to relieve symptoms of certain stomach/intestinal disorders such as "nervous stomach"; symptoms of menopause including hot flashes (flushes), sweats, restlessness and insomnia; certain types of throbbing headaches; and certain heart/blood vessel disorders such as heart palpitations or rapid heart rate.

How To Use

Take this medication by mouth, usually one in the morning and one in the evening, or take as directed by your doctor. Do not use daily on a regular basis.

Side Effects

Dizziness, drowsiness, blurred vision, nausea, constipation, heartburn, nervousness, headache, flushing, dry mouth, change in taste perception, increased sensitivity to light or a bloated feeling may occur. If any of these effects persist or worsen, inform your doctor. Notify your doctor if you develop: chest pain, rapid pulse, difficulty urinating, confusion, tremor, restlessness, skin rash, fever. In the unlikely event you have an allergic reaction to this drug, seek immediate medical attention. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.


Tell your doctor your medical history, especially of: heart problems, liver problems, glaucoma, urinary problems, Parkinson's disease, muscle problems (myasthenia gravis), ulcers, any allergies you may have. Because this drug may make you dizzy or drowsy, use caution performing tasks requiring alertness such as driving or using machinery. Limit or avoid alcohol consumption. This combination product must not be used during pregnancy. If you become pregnant or think you may be pregnant, inform your doctor immediately. This medication is excreted into breast milk and may have undesirable effects on a nursing infant. Consult your doctor before breast-feeding.

Drug Interactions

Infrequently, a very serious, life-threatening decrease in the amount of blood supply to the hands and feet (peripheral ischemia) and rarely to the brain can occur when this medication is taken with drugs that affect liver metabolism (e.g., potent CYP 3A4 enzyme inhibitors). Do not take this medication with macrolide antibiotics (e.g., erythromycin, clarithromycin, troleandomycin), HIV protease inhibitors (e.g., retonavir, nelfinavir, indinavir, amprenavir, saquinavir), azole antifungals (e.g., ketoconazole, itraconazole). Tell your doctor of all prescription and nonprescription medications you may use, especially of: digoxin, cyclosporine, saquinavir, ritonavir, sleep medicines, "triptan" drugs (e.g., sumatriptan), beta-blockers (e.g., propranolol), St John's wort, nefazodone, fluconazole, fluoxetine, fluvoxamine, zileuton, clotrimazole, other mild CYP 3A4 enzyme inhibitors. Tell your doctor if you take any drugs that make you drowsy, such as: tricyclic antidepressants (e.g., amitriptyline), narcotic pain relievers (e.g., codeine), tranquilizers, certain antihistamines found in cold medicines (e.g., diphenhydramine). Avoid eating grapefruit or drinking grapefruit juice while using this medication unless your doctor instructs you otherwise. This drug may interfere with the effectiveness of birth control pills. Discuss using other methods of birth control with your doctor. Do not start or stop any medicine without doctor or pharmacist approval.


If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include blurred vision, dilated pupils, hot and dry skin, dizziness, dryness of mouth, and slow or shallow breathing.


Do not share this medication with others.

Missed Dose

If you miss a dose, take it as soon as remembered; do not take it if it is near the time for the next dose, instead, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.


Store at room temperature between 59 and 86 degrees F (15 to 30 degrees C) away from heat and light. Do not store in the bathroom.