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Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.




WARNING: Rare (sometimes fatal) asthma-related problems have occurred with the use of products containing salmeterol. While this problem is rare, when it does occur it has affected black people more than other races. Do not stop using your medications for asthma or other breathing problems (emphysema or bronchitis) without doctor approval, since your condition will worsen if you suddenly stop your treatment. Consult your doctor or pharmacist for more details.


Salmeterol opens air passages in the lungs to improve breathing. It is used to prevent/minimize problems in persons with breathing difficulties (e.g., asthma and chronic obstructive disorders of the lungs such as chronic bronchitis or emphysema). This medication is not for use in an acute asthma attack. Salmeterol is generally combined with another effective controller-type asthma medicine (such as an inhaled corticosteroid).

How To Use

Make sure you understand how to use the device properly and how this medication should be used in relation to other asthma drugs. Refer to the illustrated directions provided by the manufacturer for instructions on the correct use of this device. Ask your pharmacist or doctor if there is anything in the illustration you do not understand. Always activate and use this device in a level, horizontal position. Usually, this medicine is used twice daily, (one inhalation in the morning and one in the evening) or use as directed by your doctor. Do not use it more frequently without your doctor's approval. If you find that your fast-acting inhaler is not working as well or if you need to use it more often than usual (i.e., using 4 or more puffs daily, or using more than 1 inhaler every 8 weeks), tell your doctor or pharmacist promptly. This may be a sign of worsening asthma which is a serious condition. You should use this medication 30 to 60 minutes before exercise when using it to prevent exercise-induced asthma. Never exhale into the device. Do not use with a spacer. Never wash the mouthpiece or any part of the device. It must be kept dry. Rinse your mouth after using to help prevent dry mouth and to relieve throat irritation. If you find your symptoms do not improve or they worsen after using this, contact your doctor immediately.

Side Effects

Dry mouth, irritated throat, dizziness, headache, lightheadedness, heartburn, loss of appetite, altered taste sensation, restlessness, anxiety, nervousness, trembling, and sweating may occur but should subside as your body adjusts to the medication. If these symptoms persist or worsen, inform your doctor. To relieve dry mouth, suck on (sugarless) hard candy or ice chips, chew (sugarless) gum, drink water or use saliva substitute. Inform your doctor if you experience: chest pain, pounding heartbeat. In the unlikely event you have an allergic reaction to this drug, seek medical attention immediately. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.


Before using this drug, tell your doctor your medical history especially of: heart disease, high blood pressure, overactive thyroid gland, epilepsy, diabetes, any drug allergies. This drug should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known if this drug is excreted into breast milk. Consult your doctor before breast-feeding.

Drug Interactions

Tell your doctor of all drugs you may use, both prescription and nonprescription including: beta-blockers (e.g., labetalol, propranolol, timolol), MAO inhibitors (e.g., furazolidone, linezolid, phenelzine, selegiline, tranylcypromine), asthma medications, antidepressants (e.g., fluoxetine, sertraline), diuretics (e.g., hydrochlorothiazide). It is important to read carefully all labels on over-the-counter preparations, especially those used to treat colds or allergies. Do not use these without first consulting your doctor. Do not start or stop any medicine without doctor or pharmacist approval.


If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include chest pain, fast or irregular heartbeat, headache, tremors, nervousness, weakness, and dizziness.


Learn to use a peak flow meter, use it daily, and promptly report worsening asthma (such as readings in yellow or red range, or increased used of quick-relief inhalers). Do not share this medication with others.

Missed Dose

Ask your doctor about what action to take if you should miss a dose. Do not 'double-up' the dose.


Store at room temperature between 68 and 77 degrees F (between 20 and 25 degrees C) away from moisture and sunlight. Do not store in the bathroom. Do not store the device for later use. Discard it after every blister has been used or 6 weeks after opening foil pouch, whichever comes first. Keep out of children's reach.

Medical Alert

Your condition can cause complications in a medical emergency. For enrollment information call MedicAlert at 1-800-854-1166 (USA), or 1-800-668-1507 (Canada).