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Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.





This medication is used to treat amyotrophic lateral sclerosis (ALS, Lou Gehrig's disease).

How To Use

Take this by mouth exactly as directed usually every 12 hours. Try to take this at the same times each day. This is best taken on an empty stomach one hour before or two hours after a meal. Do not increase the dose or take this more often than prescribed. There is no increased benefit from higher doses but the risk of side effects is increased.

Side Effects

Nausea, vomiting, stomach pain, loss of appetite, dizziness, drowsiness, weakness, diarrhea, constipation and tingling or numbness around the mouth may occur. If these symptoms continue or become severe, inform your doctor. Notify your doctor if you experience: breathing trouble, cough, fever, chills, sore throat, swelling of the hands or feet, skin rash, muscle aches. If you notice other effects not listed above, contact your doctor or pharmacist.


Before taking this, tell your doctor if you have: liver disease, kidney disease, any allergies. Use caution driving or operating machinery if this makes you drowsy or dizzy. Limit alcohol intake. This medication should be used during pregnancy only if clearly needed. Breast-feeding is not recommended while taking this drug. Discuss the risks and benefits with your doctor.

Drug Interactions

Tell your doctor of any nonprescription or prescription medication you may use, particularly: theophylline, caffeine, amitriptyline, rifampin, omeprazole, sulfasalazine, quinolone antibiotics, allopurinol, methyldopa. Do not start or stop any medicine without doctor or pharmacist approval.


If overdose is suspected, contact your local poison control center or emergency room immediately.


This medication is not a cure for ALS but has been shown to slow progression of the disease. Laboratory tests will be done routinely while taking this to monitor its effects and to prevent side effects.

Missed Dose

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.


Store at room temperature between 68 and 77 degrees F (20 to 25 degrees C) away from heat and moisture as directed. Keep this and all medications out of the reach of children.