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Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.




WARNING: If you have angina or have had heart problems, do not suddenly stop using this medication without first consulting your doctor. If your doctor decides you should no longer use this medication, you must stop this medication gradually according to your doctor's instructions.


This medication is used for temporary control of heart rate and blood pressure.

How To Use

This medication is diluted then given continuously by vein (IV infusion). Dosage is based on your medical condition and response to therapy. Follow all instructions for proper mixing and dilution. Consult your pharmacist if you are unclear on any instructions of use. Check visually for particles or discoloration before use. If present, do not use the medication.

Side Effects

Nausea and drowsiness may occur. If these effects persist or worsen, notify your doctor. Report promptly any: dizziness, sweating, pain/redness at the injection site. Unlikely but report promptly: mental/mood changes, headache, rash. Very unlikely but report promptly: chest pain, swelling, trouble breathing, unusually slow or irregular pulse, changes in skin color, fainting, seizures. If you notice other effects not listed above, contact your doctor or pharmacist.


Tell your doctor your medical history, including: any allergies, heart disease, kidney disease, low blood pressure (hypotension), breathing problems (asthma or COPD), diabetes. Limit alcohol intake, as this may intensify drug side effects. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known whether this drug is excreted into breast milk. Consult your doctor before breast-feeding.

Drug Interactions

Tell your doctor of all nonprescription and prescription medication you may use, especially: other beta-blockers (e.g., propranolol, metoprolol), "calcium channel blockers" (e.g., verapamil, diltiazem, nifedipine), digoxin, morphine, NSAIDs (e.g., ibuprofen), arbutamine, dopamine, succinylcholine, epinephrine/norepinephrine, other blood pressure medicine (e.g., reserpine, clonidine), "blood thinners" (e.g., warfarin), St John's wort. This drug can block some effects of adrenaline (epinephrine), which is a drug used to treat allergic emergencies. Consult your doctor. Also report use of drugs causing drowsiness such as: antidepressants (e.g., amitriptyline, fluoxetine, sertraline), sedatives, tranquilizers, narcotic pain relievers (e.g., codeine), certain antihistamines (e.g., diphenhydramine). Do not mix this drug with sodium bicarbonate IV fluids. Do not start or stop any medicine without doctor or pharmacist approval.


If overdose is suspected, contact your local poison control center or emergency room immediately.


Do not share this medication with others. Laboratory and/or medical tests may be performed to monitor for side effects or response to treatment.

Missed Dose

If your dose is interrupted, contact your doctor or pharmacist immediately to re-establish dosing.


Store at room temperature between 59 and 86 degrees F (15 - 30 degrees C) away from light and moisture. After mixing and dilution in IV fluids (consult your pharmacist for details), this product is stable at room temperature for 24 hours. Discard any unused product.

Medical Alert

Your condition can cause complications in a medical emergency. For enrollment information call MedicAlert at 1-800-854-1166 (USA), or 1-800-668-1507 (Canada).