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RESCRIPTOR
DELAVIRDINE - ORAL

Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.

DELAVIRDINE - ORAL

(deh-LAV-er-deen)

COMMON BRAND NAME(S): Rescriptor

Uses

This medication is used in the treatment of infection with HIV (the virus that causes AIDS). It is used in combination with other HIV medications (antiretrovirals) in selected patients.

How To Use

Take by mouth exactly as directed, usually three times a day with or without food. For ease of use, the tablets may be dissolved in water before swallowing. To dissolve the drug, add the tablets for the next dose to at least 3 ounces (90 cc) of water, allow to stand for a few minutes, and then stir. The liquid should be consumed promptly. The glass should be rinsed and the rinse swallowed to be sure the whole dose of medicine is taken. If taking didanosine or antacids, take them one hour apart from this drug. For anyone with lack of stomach acid (achlorhydria), take this drug with an acidic beverage (e.g., orange or cranberry juice).

Side Effects

Headache or nausea might occur. If these persist or worsen, notify your doctor. Report to your doctor promptly: rash, itching. Unlikely but report promptly: vomiting, stomach pain, yellowing skin or eyes, fever, trouble breathing, swelling, dizziness/fainting, persistent sore throat, unusual bleeding or bruising. Changes in body fat may occur while you are taking this medication (e.g., increased fat in the upper back and stomach areas, decreased fat in the arms and legs). The cause and long-term effects of these changes are unknown. Discuss the risks and benefits of therapy with your doctor, as well as the possible role of exercise to reduce this side effect. If you notice other effects not listed above, contact your doctor or pharmacist.

Precautions

Before taking this drug, tell your doctor your entire medical history, including: allergies (particularly drug allergies), liver disease. Report promptly to your doctor: severe rash, rash with symptoms (e.g., fever, blistering, mouth sores, swelling, muscle/joint aches). This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known whether this drug is excreted into human milk. Avoid breast-feeding to prevent transmission of HIV infection to an uninfected infant. Caution is advised when using this drug in children under 16 years of age.

Drug Interactions

This drug is not recommended for use with: rifabutin, rifampin. Ask your doctor or pharmacist for more details. Tell your doctor of all nonprescription and prescription medication you may take, especially: antacids (containing aluminum and magnesium), clarithromycin, fluoxetine, ketoconazole, phenytoin, phenobarbital, carbamazepine, terfenadine, astemizole, dapsone, ergot derivatives (e.g., cafergot, ergotamine), alprazolam, midazolam, triazolam, nifedipine-like calcium channel blockers, cisapride, quinidine, warfarin, amphetamines, H2 blockers (e.g., cimetidine), St John's wort, sildenafil, protease inhibitors (e.g., amprenavir), didanosine. Do not start or stop any medicine without doctor or pharmacist approval.

Overdose

If overdose is suspected, contact your local poison control center or emergency room immediately.

Notes

Do not share this medication with anyone else. This medication has not been shown to reduce the chance of transmitting HIV to others.

Missed Dose

If you miss a dose, use it as soon as you remember. If it is within 2 hours of the next dose, skip the missed dose and resume your usual dosing schedule. It is important not to miss doses of this drug.

Storage

Store at room temperature between 68 and 77 degrees F (20-25 degrees C) away from light and moisture. Keep container tightly closed.

Medical Alert

Your condition can cause complications in a medical emergency. For enrollment information call MedicAlert at 1-800-854-1166 (USA), or 1-800-668-1507 (Canada).