Find & Manage Your Patient Assistance Programs
Estimated patient savings $600,000,000.00

Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.





Metoclopramide is used for nausea, vomiting, heartburn, loss of appetite, bloating and gastric reflux.

How To Use

This medication is injected into a vein (IV) or into a muscle (IM) as directed by your doctor. The dosage depends on your condition and response to the medication. Metoclopramide works best when used 30 minutes before a meal. Do not use this more often or in larger doses than prescribed by your doctor.

Side Effects

Nausea, diarrhea, headache, dizziness, drowsiness, dry mouth, restlessness or sleeplessness may occur. If any of these effects persist or worsen, inform your doctor. Notify your doctor if you experience: uncontrolled movements of the face/eyes or limbs, muscle spasms, trembling of the hands, any personality changes (such as depression). In the unlikely event you have an allergic reaction to this drug, seek immediate medical attention. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.


Tell your doctor your medical history, especially of: adrenal tumors, seizure disorders, Parkinson's disease, high blood pressure, heart disease, liver or kidney disease, mental conditions/depression, stomach/intestinal problems (e.g., bleeds or blockages), diabetes, asthma, any allergies. Use caution engaging in activities requiring alertness such as driving or using machinery if this medication makes you drowsy. Alcoholic beverages can add to the drowsiness effect caused by this drug. Avoid alcohol while using this medication. Tell your doctor if you are pregnant before using this drug. Metoclopramide is excreted into breast milk. Though there have been no reports (to date) of harm to nursing infants, consult your doctor before breast-feeding.

Drug Interactions

Tell your doctor of all medicines you may use (both prescription and nonprescription), especially: cimetidine, insulin, cabergoline, cyclosporine, digoxin, levodopa, MAO inhibitors (e.g., furazolidone, linezolid, moclobemide, phenelzine, procarbazine, selegiline, tranylcypromine). Tell your doctor if you take any drugs that make you drowsy such as: narcotic pain medication (e.g., codeine), tranquilizers, sleep medicine, antidepressants, drowsiness-causing antihistamines (e.g., diphenhydramine), sedatives, alcoholic beverages. Before having surgery with a general anesthetic, including dental surgery, tell the doctor or dentist you use metoclopramide. Do not start or stop any medicine without doctor or pharmacist approval.


If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include drowsiness, disorientation, twitching of the face or tongue, loss of balance, uncontrolled movements of arms and legs, and difficulty speaking and swallowing.


Do not share this medication with others.

Missed Dose

If you miss a dose, use it as soon as remembered; do not use if it is almost time for the next dose, instead, skip the missed dose and resume your usual dosing schedule. Do not "double- up" the dose to catch up.


Store undiluted doses at room temperature between 68 and 78 degrees F (between 20 and 25 degrees C) away from moisture and sunlight. Do not store in the bathroom. Once diluted, doses must be used within 24 hours. Discard after 24 hours. Do not save for later use because they contain no preservatives.