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Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.





Pantoprazole injection is a proton pump inhibitor (PPI)used to treat acid-related stomach problems (e.g., esophagitis, ulcers) in people who cannot take or tolerate the oral form of this medication.

How To Use

Follow all instructions for the proper mixing and dilution with the correct IV fluids. If you have any questions regarding the use of this medication, consult your pharmacist. Give this medication by vein (IV) over at least 15 minutes in a proper IV solution, usually once daily or as directed by your doctor. Consult your pharmacist for the correct IV fluid to use. The dosage is based on your medical condition and response to therapy. This medication may contain small particles after it is added to the IV solution. It is very important to use the IV filter (as an "in-line" filter) that is provided with this medication while giving the solution. Consult your pharmacist for the proper use of this filter. When you are able to take oral medications, your doctor will switch your treatment to an oral form of this drug. Learn how to store and discard needles and medical supplies safely. Consult your pharmacist.

Side Effects

Headache, nausea, heartburn, dizziness, or redness/swelling and pain at the injection site may occur. If any of these effects persist or worsen, notify your doctor. Tell your doctor immediately if any of these serious side effects occur: stomach pain, chest pain, rash, itching, vomiting. Tell your doctor immediately if any of these unlikely but serious side effects occur: yellowing eyes and skin, severe stomach pain, dark urine, fatigue, fever, vision problems, mental/mood changes. An allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include: rash, itching, swelling, severe dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.


Tell your doctor your medical history, especially of: liver problems, any allergies (especially to similar ulcer drugs such as omeprazole, lansoprazole, or rabeprazole). This medication may make you dizzy; use caution engaging in activities requiring alertness such as driving or using machinery. Limit alcoholic beverages. Tell your doctor if you are pregnant before using pantoprazole. It is not known if pantoprazole passes into breast milk. Consult your doctor before breast-feeding.

Drug Interactions

Tell your doctor of all prescription and nonprescription medication you may use, especially: azole antifungals (e.g., itraconazole, ketoconazole), ampicillin, digoxin, iron-containing products (e.g., iron supplements, vitamins with iron). This medication may affect the results of certain lab tests (e.g., false positive urine screen for THC). Make sure laboratory personnel and your doctors know you use this drug. Do not start or stop any medicine without doctor or pharmacist approval.


If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose include: severe loss of coordination, tremor.


Do not share this medication with others. Laboratory and/or medical tests may be performed to monitor your progress.

Missed Dose

If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.


Store the vials at refrigerated temperature between 36 and 46 degrees F (2 to 8 degrees C) away from light and moisture. After mixing, the vial solution is good for 2 hours at room temperature (between 59 and 86 degrees F or 15 and 30 degrees C). Discard any unused portion of the vial. After mixing and subsequent dilution in IV fluids, this product is stable for up to 12 hours at room temperature. Do not freeze. The filter for this product should be stored at room temperature.