Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.

NEOSTIGMINE BROMIDE - ORAL

(nee-oh-STIG-min)

COMMON BRAND NAME(S): Prostigmin

Uses

This medication is a muscle stimulant used in the treatment of muscle diseases such as myasthenia gravis. Also used to counteract the effects of certain muscle relaxant medications.

How To Use

Take this medication by mouth as directed usually in multiple doses throughout the day and night. It is important to keep a record of all doses taken and how you are feeling so adjustments can be made if necessary. Note any periods of fatigue or muscle weakness. Do not increase your dose or take this more often than directed as serious side effects can occur.

Side Effects

Vision changes, stomach upset, flushing, flatulence, dizziness, drowsiness, muscle cramps, muscle twitching or increased urination may occur. These effects should subside as your body adjusts to the medication. If they continue or become bothersome, inform your doctor. Notify your doctor if you develop: nausea, vomiting, severe stomach pains, diarrhea, sweating, increased salivation, irregular heartbeat, muscle weakness, difficulty speaking or swallowing, breathing difficulties. If you notice other effects not listed above, contact your doctor or pharmacist.

Precautions

Tell your doctor if you have a history of: asthma, seizure disorder, heart disease, thyroid disorders, intestinal disorders, ulcers, urinary problems, allergies (especially allergy to bromides). Because this medication can cause dizziness or drowsiness, use caution engaging in activities that require alertness such as driving or using machinery. This medication should be used only if clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known if this medication appears in breast milk, consult your doctor before breast-feeding.

Drug Interactions

Tell your doctor of any over-the-counter or prescription medication you use, especially of: antibiotics, other muscle stimulants, steroids, muscle relaxants, heart medications, magnesium. Do not start or stop any medicine without doctor or pharmacist approval.

Overdose

If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include stomach cramps, diarrhea, vomiting, excess saliva, blurred vision, and difficulty swallowing.

Notes

Inform your doctor if you feel this medication is not as effective as it once was. Some patients may experience lack of sensitivity to the medication which requires a reduced dose or stopping therapy for a period of time. Discuss this with your doctor.

Missed Dose

For best results, it is important to take each dose as prescribed. However, if you miss a dose, take it as soon as remembered; do not take it if it is near the time for the next dose, instead, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.

Storage

Store at room temperature between 59 and 86 degrees F (15 and 30 degrees C) away from heat and light. Do not store in the bathroom.

Medical Alert

Your condition can cause complications in a medical emergency. For enrollment information call MedicAlert at 1-800-854-1166 (USA), or 1-800-668-1507 (Canada).