Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.

FACTOR IX, HUMAN - INJECTION

(FACK-ter nine)

COMMON BRAND NAME(S): Alphanine SD, Bebulin VH Immuno, Konyne 80, Proplex T

WARNING: Because this medication is made from human blood, it is possible you may develop infections from it (e.g., hepatitis, viral infections). Notify your doctor immediately if you develop any signs of an infection or hepatitis. Signs include fever, persistent sore throat, unusual fatigue, yellowing eyes or skin, or dark urine. You may develop blood clots with the use of this medication. Notify your doctor if you develop arm or leg pain/swelling, trouble breathing, or chest pain. This medication is not recommended for use if you have liver disease complicated by blood-clotting problems (disseminated intravascular coagulation-DIC, or fibrinolysis).

Uses

Factor IX is a part of blood needed for clotting which stops bleeding. Persons with low Factor levels are at risk for bleeding. This medication is used to prevent or control bleeding episodes in persons with low Factor levels (hemophilia, Christmas disease). It is also used to reverse the effects of warfarin blood thinner.

How To Use

This medication is given by injection by a health care professional. The dose and length of therapy is based on your condition and response.

Side Effects

Fever, chills, tingling, itching, headache, flushing, nausea and vomiting have been reported. If any of these effects continue or become bothersome, inform your doctor. Notify your doctor if you develop: chest pain, breathing trouble, redness/pain/warmth in the calf, skin rash. If you notice other effects not listed above, contact your doctor or pharmacist.

Precautions

Tell your doctor if you have: other illnesses, liver problems, allergies (especially drug allergies). Remind your doctor you are using this medication if you are scheduled for any surgical or dental procedures. Because this medication is prepared from human blood, there is a risk of contracting a virus from using this. Careful screening of blood donors, special manufacturing methods and FDA-approved tests are all used to reduce this risk. Discuss this with your doctor. This medication should be used only if clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known if this medication is found in breast milk. Consult your doctor before breast-feeding.

Drug Interactions

Tell your doctor of any over-the-counter or prescription medication you use, especially of: drugs that aid blood clotting (e.g., tranexamic acid, aminocaproic acid), NSAIDs - non-steroidal anti-inflammatory drugs (e.g., aspirin, ibuprofen). Many non-prescription products contain aspirin/NSAIDs. Check labels carefully and consult your pharmacist. Do not start or stop any medicine without doctor or pharmacist approval.

Overdose

If overdose is suspected, contact your local poison control center or emergency room immediately.

Notes

Laboratory tests may be done periodically while taking this medication to monitor its effects and guide therapy.

Missed Dose

If you miss a dose, check with your doctor for instructions.

Storage

Store this medication according to the manufacturer's instructions.

Medical Alert

Your condition can cause complications in a medical emergency. For enrollment information call MedicAlert at 1-800-854-1166 (USA), or 1-800-668-1507 (Canada).