Find & Manage Your Patient Assistance Programs
Estimated patient savings $600,000,000.00

Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.


(poh-TASS-ee-um GWEYE-uh-koll-SULL-fun-ate W/dex-trow-meth-OR-fan)



This combination of cough suppressant and expectorant medicines is used to treat cough due to colds, flu or hay fever. Also, phlegm (lung secretions) may become less thick after using this medication along with fluids.

How To Use

Take this medication by mouth generally 4 times daily with a full glass (8 oz or 240 ml) of water as needed, or as directed by your doctor. Drink plenty of fluids unless otherwise directed. Notify your doctor if your condition does not improve in 7 days or if you develop a high fever or persistent headache.

Side Effects

Nausea, drowsiness or dizziness may occur. If these effects persist or worsen, notify your doctor. If you notice other side effects not listed above, contact your doctor or pharmacist.


Tell your doctor your medical history, including: allergies (especially drug allergies). This medication may make you dizzy or drowsy; use caution engaging in activities requiring alertness such as driving or using machinery. Limit alcoholic beverages. This medication should not be given to children under 3 years of age. Ask your doctor or pharmacist for more details. This combination of medications should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known whether this combination of medications passes into breast milk. Because of the potential risk to the infant, breast-feeding while using this product is not recommended. Consult your doctor before breast-feeding.

Drug Interactions

Tell your doctor of all prescription and nonprescription drugs you use, especially of: MAO inhibitors used currently or stopped within the last 2 weeks (e.g., furazolidone, linezolid, moclobemide, phenelzine, procarbazine, selegiline). Also report the use of drugs that cause drowsiness, such as: sleeping pills, tranquilizers, anti-anxiety drugs, narcotic pain relievers (e.g., codeine), psychiatric medicines, anti-seizure drugs, muscle relaxants, sedatives, antihistamines that cause drowsiness (e.g., diphenhydramine). Check the labels on all your medicines (e.g., cough-and-cold products) because they may contain drowsiness-causing ingredients. Ask your pharmacist about the safe use of those products. Do not start or stop any medicine without doctor or pharmacist approval.


If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include nausea, vomiting, drowsiness, blurred vision, slowed breathing, and seizures.


Do not share this product with others.

Missed Dose

When instructed to use this on a regular schedule (not "as needed"): if you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.


Store at room temperature between 59 and 86 degrees F (15-30 degrees C) away from light and moisture.